Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50019621
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206281(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206272(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206279(5-chloro-4-(1H-indol-6-yl)-N-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206285(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206271(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50: 37nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206281(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 48nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50: 69nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206278(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 76nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206284(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 103nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-ARYL-2-PHENYLAMINO PYRIMIDINE | 4-(4-(2-aminopro...)
Affinity DataIC50: 148nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50: 159nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50: 180nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206273(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 216nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206274(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 314nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206270(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 334nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50: 348nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50: 439nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206270(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 455nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50: 461nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206273(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 540nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50: 687nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206274(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 781nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50: 797nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206271(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 808nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206284(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 847nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206285(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206279(5-chloro-4-(1H-indol-6-yl)-N-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206278(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206272(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-ARYL-2-PHENYLAMINO PYRIMIDINE | 4-(4-(2-aminopro...)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed