Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50037935
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206106((8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4...)
Affinity DataIC50: 0.270nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206114((8S,11R,13S,14R,17S)-17-(4-chloro-phenylethynyl)-1...)
Affinity DataIC50: 0.610nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206108((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 0.75nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206097((8S,11R,13S,14R,17S)-17-(3,5-difluoro-phenylethyny...)
Affinity DataIC50: 0.910nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206109((8S,11R,13S,14R,17S)-17-(4-bromo-phenylethynyl)-11...)
Affinity DataIC50: 0.940nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206101((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206098((8S,11R,13S,14R,17S)-17-(2-chloro-phenylethynyl)-1...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200660((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206100((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206107((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206115((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206102((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206111((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206117((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206104((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206113(4-[(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206099((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200655((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206103((8S,11R,13S,14R,17S)-17-(2-bromo-phenylethynyl)-11...)
Affinity DataIC50: 8.60nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206112((8S,11R,13S,14R,17S)-17-(3-chloro-phenylethynyl)-1...)
Affinity DataIC50: 12.5nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206116((8S,11R,13S,14R,17S)-17-(4-tert-butyl-phenylethyny...)
Affinity DataIC50: 19.5nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206110((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206107((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 22.1nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206109((8S,11R,13S,14R,17S)-17-(4-bromo-phenylethynyl)-11...)
Affinity DataIC50: 31.3nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206105((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206097((8S,11R,13S,14R,17S)-17-(3,5-difluoro-phenylethyny...)
Affinity DataIC50: 34.4nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206111((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 36.3nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206106((8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4...)
Affinity DataIC50: 37.6nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206096((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206113(4-[(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl...)
Affinity DataIC50: 41.3nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206114((8S,11R,13S,14R,17S)-17-(4-chloro-phenylethynyl)-1...)
Affinity DataIC50: 43.5nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206102((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 45.4nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206112((8S,11R,13S,14R,17S)-17-(3-chloro-phenylethynyl)-1...)
Affinity DataIC50: 48.9nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206104((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206115((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206101((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 56.6nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206103((8S,11R,13S,14R,17S)-17-(2-bromo-phenylethynyl)-11...)
Affinity DataIC50: 62.7nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206098((8S,11R,13S,14R,17S)-17-(2-chloro-phenylethynyl)-1...)
Affinity DataIC50: 64.8nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206100((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 65.1nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206116((8S,11R,13S,14R,17S)-17-(4-tert-butyl-phenylethyny...)
Affinity DataIC50: 65.8nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206117((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 80.3nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200655((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...)
Affinity DataIC50: 86.5nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206108((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 111nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206099((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206105((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 175nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206096((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 247nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50200660((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...)
Affinity DataIC50: 304nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50206110((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...)
Affinity DataIC50: 342nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed