Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50019541
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205684(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  0.270nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205686(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  0.530nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205677(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  1.30nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205682(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  6nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205683(1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataKi:  6.5nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205679(N1-benzyl-N3-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)...)
Affinity DataKi:  15nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205678(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  23nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205685(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  29nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205681(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  96nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205680(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataKi:  280nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205686(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205679(N1-benzyl-N3-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205678(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205683(1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenylet...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205684(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205681(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205682(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205677(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205685(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50205680(N1-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phenyle...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed