Compile Data Set for Download or QSAR
Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 50019539
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205667(4-(2-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1...)
Affinity DataKi:  1nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205656(4-phenyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tet...)
Affinity DataKi:  1nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205654(4-(4-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1...)
Affinity DataKi:  2nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205655(4-(2-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)p...)
Affinity DataKi:  2nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205662(7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methox...)
Affinity DataKi:  4nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205645(N,N-diethyl-3-(6-methyl-8-phenyl-5,6,7,8-tetrahydr...)
Affinity DataKi:  4nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205653(4-(4-methoxyphenyl)-7-(3-(piperidin-1-yl)propoxy)-...)
Affinity DataKi:  4nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205644(2-methyl-4-phenyl-7-(3-(piperidin-1-yl)propoxy)-1,...)
Affinity DataKi:  5nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205669(4-(3,4-dichlorophenyl)-7-(3-(piperidin-1-yl)propox...)
Affinity DataKi:  5nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205665(4-(3-chlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)p...)
Affinity DataKi:  7nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205660(4-(4-chloro-3-fluorophenyl)-2-methyl-7-(3-(piperid...)
Affinity DataKi:  7nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205658(3-(8-(3,4-dichlorophenyl)-5,6,7,8-tetrahydro-2,6-n...)
Affinity DataKi:  7nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205664(4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  8nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205657(4-(4-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)p...)
Affinity DataKi:  9nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205668(4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  12nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205663(7-(3-morpholinopropoxy)-4-phenyl-1,2,3,4-tetrahydr...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205661(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205646(7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methox...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205647(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205652(N,N-diethyl-3-(8-(4-methoxyphenyl)-6-methyl-5,6,7,...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205651(4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-...)
Affinity DataKi:  15nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205662(7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methox...)
Affinity DataKi:  15nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205658(3-(8-(3,4-dichlorophenyl)-5,6,7,8-tetrahydro-2,6-n...)
Affinity DataKi:  15nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205650(4-(4-chlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)p...)
Affinity DataKi:  15nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205648(3-(8-(3,4-dichlorophenyl)-6-methyl-5,6,7,8-tetrahy...)
Affinity DataKi:  16nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205651(4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-...)
Affinity DataKi:  18nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205661(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205652(N,N-diethyl-3-(8-(4-methoxyphenyl)-6-methyl-5,6,7,...)
Affinity DataKi:  19nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205669(4-(3,4-dichlorophenyl)-7-(3-(piperidin-1-yl)propox...)
Affinity DataKi:  20nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205650(4-(4-chlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)p...)
Affinity DataKi:  22nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205647(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  23nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205666(N,N-diethyl-3-(8-(4-methoxyphenyl)-5,6,7,8-tetrahy...)
Affinity DataKi:  23nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205658(3-(8-(3,4-dichlorophenyl)-5,6,7,8-tetrahydro-2,6-n...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205660(4-(4-chloro-3-fluorophenyl)-2-methyl-7-(3-(piperid...)
Affinity DataKi:  26nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205659(4-(4-methoxyphenyl)-2-methyl-7-(3-morpholinopropox...)
Affinity DataKi:  29nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205648(3-(8-(3,4-dichlorophenyl)-6-methyl-5,6,7,8-tetrahy...)
Affinity DataKi:  30nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205654(4-(4-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1...)
Affinity DataKi:  30nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205647(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205669(4-(3,4-dichlorophenyl)-7-(3-(piperidin-1-yl)propox...)
Affinity DataKi:  32nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205648(3-(8-(3,4-dichlorophenyl)-6-methyl-5,6,7,8-tetrahy...)
Affinity DataKi:  33nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205668(4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  34nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205661(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  37nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205649(4-(4-methoxyphenyl)-7-(3-morpholinopropoxy)-1,2,3,...)
Affinity DataKi:  43nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205646(7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methox...)
Affinity DataKi:  45nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205653(4-(4-methoxyphenyl)-7-(3-(piperidin-1-yl)propoxy)-...)
Affinity DataKi:  46nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205649(4-(4-methoxyphenyl)-7-(3-morpholinopropoxy)-1,2,3,...)
Affinity DataKi:  53nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205664(4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  59nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205646(7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methox...)
Affinity DataKi:  62nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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