Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50018915
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200240(4-(4-(4-chlorobenzyl)piperazin-1-yl)-N-(2,4-dichlo...)
Affinity DataIC50: 280nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200236(4-(4-(4-chlorobenzyl)piperazin-1-yl)-N-(4-chloroph...)
Affinity DataIC50: 370nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200237(4-(4-(3,4-dichlorobenzyl)piperazin-1-yl)-N-(2,4-di...)
Affinity DataIC50: 750nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200220(4-(4-(3-chlorophenyl)piperazin-1-yl)-N-(2,4-dichlo...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200239(5-(4-(3,4-dichlorobenzyl)piperazin-1-yl)-N-(2-chlo...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50117922(CHEMBL45816 | Methoxy-acetic acid 2-(2-{[3-(1H-ben...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200229(4-(4-(3-chlorobenzyl)piperazin-1-yl)-N-(2,4-dichlo...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200227(4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200241(4-(4-(3-chlorobenzyl)piperazin-1-yl)-N-(4-chloroph...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200246(5-(4-(4-chlorobenzyl)piperazin-1-yl)-1-(4-(2-fluor...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200244(N-(2-chlorophenyl)-5-(4-(3-chlorophenyl)piperazin-...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200219(4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-N-(2...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200225(5-(4-(3-chlorobenzyl)piperazin-1-yl)-1-(4-(2-fluor...)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200238(N-(4-chlorophenyl)-4-(4-(2-methoxyphenyl)piperazin...)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200223(N-(4-chlorophenyl)-4-(4-(4-chlorophenyl)piperazin-...)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200245(4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200234(N-(4-chlorophenyl)-4-(4-(3-methoxyphenyl)piperazin...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200231(5-(4-(3,4-dichlorobenzyl)piperazin-1-yl)-1-(4-phen...)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200242(4-(4-benzylpiperazin-1-yl)-N-(2,4-dichlorophenyl)b...)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200230(4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-N-(4...)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200226(N-(2,4-dichlorophenyl)-4-(4-(2-methoxyphenyl)piper...)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200224(5-(4-(4-chlorobenzyl)piperazin-1-yl)-1-(4-phenylpi...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200228(N-(4-chlorophenyl)-4-(4-(4-fluorophenyl)piperazin-...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200233(4-(4-benzylpiperazin-1-yl)-N-(4-chlorophenyl)butan...)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200243(N-(4-chlorophenyl)-4-(4-(2-fluorophenyl)piperazin-...)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200235(N-(2,4-dichlorophenyl)-4-(4-(3-methoxyphenyl)piper...)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200221(N-(2,4-dichlorophenyl)-4-(4-phenylpiperazin-1-yl)b...)
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200222(N-(4-chlorophenyl)-4-(4-phenylpiperazin-1-yl)butan...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50200232(N-(4-chlorophenyl)-4-(4-(2-chlorophenyl)piperazin-...)
Affinity DataIC50: 6.01E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha-1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed