Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50018809
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199068(3-cyano-N-(2-hydroxyethyl)-6-methoxy-4-phenylisoqu...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199064(2-{3-hydroxy-2-[(pyridin-3-ylmethyl)amino]propyl}-...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199066(1-{[(2R)-2,3-dihydroxypropyl]oxy}-6-methoxy-4-phen...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199065(3-((dimethylamino)methyl)-6-methoxy-2-methyl-4-phe...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199069(2-(2,3-dihydroxypropyl)-6-methoxy-1-oxo-4-[3-(trif...)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199060(4-(3-fluorophenyl)-6-methoxy-1-(4-methyl-1H-imidaz...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199062(1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-ph...)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199067(4-(3-fluorophenyl)-2-(2-hydroxyethyl)-6-methoxy-1-...)
Affinity DataIC50: 690nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199063(4-(3-fluorophenyl)-6-methoxy-2-{2-[(2-methoxyethyl...)
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199071(2-(2,3-dihydroxypropyl)-4-(3-fluorophenyl)-6-metho...)
Affinity DataIC50: 870nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199070(2-[(2S)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phe...)
Affinity DataIC50: 1.01E+3nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199061(2-[(2R)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phe...)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199063(4-(3-fluorophenyl)-6-methoxy-2-{2-[(2-methoxyethyl...)
Affinity DataIC50: 1.65E+3nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199065(3-((dimethylamino)methyl)-6-methoxy-2-methyl-4-phe...)
Affinity DataIC50: 5.30E+3nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199064(2-{3-hydroxy-2-[(pyridin-3-ylmethyl)amino]propyl}-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199062(1-{[(2S)-2,3-dihydroxypropyl]amino}-6-methoxy-4-ph...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199069(2-(2,3-dihydroxypropyl)-6-methoxy-1-oxo-4-[3-(trif...)
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199066(1-{[(2R)-2,3-dihydroxypropyl]oxy}-6-methoxy-4-phen...)
Affinity DataIC50: 2.05E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199060(4-(3-fluorophenyl)-6-methoxy-1-(4-methyl-1H-imidaz...)
Affinity DataIC50: 2.10E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199068(3-cyano-N-(2-hydroxyethyl)-6-methoxy-4-phenylisoqu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199071(2-(2,3-dihydroxypropyl)-4-(3-fluorophenyl)-6-metho...)
Affinity DataIC50: 3.35E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199067(4-(3-fluorophenyl)-2-(2-hydroxyethyl)-6-methoxy-1-...)
Affinity DataIC50: 6.20E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199061(2-[(2R)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phe...)
Affinity DataIC50: 7.60E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199070(2-[(2S)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phe...)
Affinity DataIC50: 1.35E+5nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed