Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50018515
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM15797(3-N-[(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-{[...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196587(benzyl 1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydro...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196587(benzyl 1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydro...)
Affinity DataIC50: 112nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human BACE in HEK293 cells by Swedish amyloid inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196582(N1-((2S,3R)-4-(3-iodobenzylamino)-3-hydroxy-1-phen...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 314nMAssay Description:Inhibition of human BACE in HEK293 cells by Swedish amyloid inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 484nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196578(3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZY...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 596nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196576(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196580(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196592(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196584(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196591(N-((2S,3R)-4-(3-iodobenzylamino)-1-(3,5-difluoroph...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196575(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196574(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196576(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196580(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196589(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196583(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196589(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 6.04E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196577(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196592(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196579(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196581(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 7.95E+3nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196586(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 9.67E+3nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196583(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196588(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196581(N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxy-benzyla...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196590(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196585(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196584(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196585(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196590(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196575(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196579(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196577(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50196588(N-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed