Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 3561
TargetSerine/threonine-protein kinase PLK1(Human)
University of Cambridge

LigandPNGBDBM8053(4-{[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-y...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:D. melanogaster Polo kinase assays were performed as previously described40, using baculovirus-expressed Polo kinase. Enzyme was immunoprecipitated u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
University of Cambridge

LigandPNGBDBM8054(4-[4-(4-Methyl-2-methylaminothiazol-5-yl)pyrimidin...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:D. melanogaster Polo kinase assays were performed as previously described40, using baculovirus-expressed Polo kinase. Enzyme was immunoprecipitated u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
University of Cambridge

LigandPNGBDBM8055(4-[4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yla...)
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:D. melanogaster Polo kinase assays were performed as previously described40, using baculovirus-expressed Polo kinase. Enzyme was immunoprecipitated u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed