Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50018305
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194233((+)-N-{(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.120nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194219((+)-(2R)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-me...)
Affinity DataIC50: 0.150nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194232((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.390nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194235((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194231((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.420nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194227((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.450nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194223((+)-1-(4-fluorophenyl)-N-[(1S,4R,5R,7S)-5-(3-hydro...)
Affinity DataIC50: 0.450nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194230((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.480nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194224((+)-N-{(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.5nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194228((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.680nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194234((+)-N-{(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.720nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194225((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 0.800nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194221((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 1.40nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194229((+)-2-ethyl-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4...)
Affinity DataIC50: 1.80nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194218((+)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl...)
Affinity DataIC50: 1.80nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194222((-)-N-(1S,4R,5R,7S)-{5-(3-hydroxy)phenyl-4-methyl-...)
Affinity DataIC50: 7.70nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194226((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-...)
Affinity DataIC50: 16nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001680(2-[2-(4-{4-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 83nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50194220((+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-2,4-dimet...)
Affinity DataIC50: 95nMAssay Description:Inverse agonist activity at human cloned delta opioid receptor expressed in CHO cells assessed as inhibition of DPDPE-stimulated [35S]GTP-gamma-S bin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed