Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 1396
TargetReplicase polyprotein 1ab(SARS-CoV)
Taigen Biotechnology

LigandPNGBDBM11233(benzyl N-[(1S,2S)-2-(tert-butoxy)-1-{[(1S)-2-cyclo...)
Affinity DataKi:  53nM ΔG°:  -41.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Taigen Biotechnology

LigandPNGBDBM11232(ethyl (2E,4S)-4-[(2S)-2-[(2S,3S)-2-{[(benzyloxy)ca...)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Taigen Biotechnology

LigandPNGBDBM11231(N-[(benzyloxy)carbonyl]-L-valyl-N1-((1S,2E)-4-etho...)
Affinity DataKi:  660nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Taigen Biotechnology

LigandPNGBDBM11230(ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbo...)
Affinity DataKi:  2.26E+3nM ΔG°:  -32.2kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Taigen Biotechnology

LigandPNGBDBM11229(AG7088 analogue 2a | CHEMBL20636 | N-[(5-methyliso...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed