Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000601
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 3.90nMAssay Description:Compound was tested for the binding affinity against sigma receptor by using [3H]-+3PPP as radioligandMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 100nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 110nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptor by using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131677(CHEMBL106970)
Affinity DataIC50: 130nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 135nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131671(CHEMBL104625)
Affinity DataIC50: 220nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 238nMAssay Description:Compound was tested for the binding affinity against 5-hydroxytryptamine 1A receptor by using [3H]DPAT as radioligandMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007676(CHEMBL553596 | CHEMBL18222 | 4-Benzyl-1-phenethyl-...)
Affinity DataIC50: 347nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131674(CHEMBL321349)
Affinity DataIC50: 400nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131542(CHEMBL102242)
Affinity DataIC50: 573nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 610nMAssay Description:Compound was tested for the binding affinity against 5-hydroxytryptamine 2 receptor by using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 843nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against opioid receptor mu by using [3H]naloxone as radioligandMore data for this Ligand-Target Pair
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PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against muscarinic acetylcholine receptor
by using [3H]QNB as radioligandMore data for this Ligand-Target Pair
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PubMed
TargetD(1A) dopamine receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against dopamine receptor D1 by using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
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PubMed
TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against histamine H1 receptor by using [3H]mepyramine as radioligandMore data for this Ligand-Target Pair
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PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against dopamine receptor D2 by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131540(CHEMBL106969)
Affinity DataIC50: 2.13E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 2.31E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131673(CHEMBL323338)
Affinity DataIC50: 2.57E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131662(CHEMBL104363)
Affinity DataIC50: 2.87E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131676(CHEMBL262807)
Affinity DataIC50: 4.63E+3nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131672(CHEMBL102212)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131675(CHEMBL322633)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131541(CHEMBL104318)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50131543(CHEMBL318347)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
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PubMed