Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50017922
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3535(4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diam...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188464(4-[(3-methylphenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188456(1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quina...)
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188461(1-(2-chloroethyl)-3-{[4-(3-chlorophenyl)amino]quin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(CHEMBL52765 | 4-N-(3-bromophenyl)quinazoline-4,6-d...)
Affinity DataIC50: 44nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188468(1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)a...)
Affinity DataIC50: 47nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188466(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-chlorophenyl)...)
Affinity DataIC50: 67nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188459(3-(2-chloroethyl)-1-methyl-1-{[4-(3-chlorophenyl)a...)
Affinity DataIC50: 81nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188462(3-(2-chloroethyl)-1-methyl-1-{[4-(3-bromophenyl)am...)
Affinity DataIC50: 156nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3535(4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diam...)
Affinity DataIC50: 170nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133382(CHEMBL343352 | N4-(3-chlorophenyl)-4,6-quinazoline...)
Affinity DataIC50: 200nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188458(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-chlo...)
Affinity DataIC50: 204nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188457(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-brom...)
Affinity DataIC50: 294nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(CHEMBL52765 | 4-N-(3-bromophenyl)quinazoline-4,6-d...)
Affinity DataIC50: 670nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188465(1-(2-chloroethyl)-3-{[4-(3-methylphenyl)amino]quin...)
Affinity DataIC50: 676nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188458(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-chlo...)
Affinity DataIC50: 680nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50: 890nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133384(N4-(3-methylphenyl)-4,6-quinazolinediamine | Anili...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188460(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-methylphenyl)...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188467(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-meth...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188468(1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)a...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188461(1-(2-chloroethyl)-3-{[4-(3-chlorophenyl)amino]quin...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188455(3-(2-chloroethyl)-1-methyl-1-{[4-(3-methylphenyl)a...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188456(1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quina...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188464(4-[(3-methylphenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188465(1-(2-chloroethyl)-3-{[4-(3-methylphenyl)amino]quin...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188457(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-brom...)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133382(CHEMBL343352 | N4-(3-chlorophenyl)-4,6-quinazoline...)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188466(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-chlorophenyl)...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133384(N4-(3-methylphenyl)-4,6-quinazolinediamine | Anili...)
Affinity DataIC50: 6.39E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188467(1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-meth...)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188462(3-(2-chloroethyl)-1-methyl-1-{[4-(3-bromophenyl)am...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188455(3-(2-chloroethyl)-1-methyl-1-{[4-(3-methylphenyl)a...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188460(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-methylphenyl)...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188459(3-(2-chloroethyl)-1-methyl-1-{[4-(3-chlorophenyl)a...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of serum-stimulated proliferation of mouse ERBB2 transfected NIH3T3 cell line after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed