Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50037711
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKd:  2.00E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKd:  3.75E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKd:  290nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(N-(4-methoxyphenyl)sulfamide | 4-methoxyphenylsulf...)
Affinity DataKd:  2.65E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50098106(CHEMBL24259 | phenyl sulfamate | Sulfamic acid phe...)
Affinity DataKd:  110nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163317(Sulfamic acid chroman-2-ylmethyl ester | (3,4-dihy...)
Affinity DataKd:  140nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163319(N-(3,4-dihydro-2H-chromen-2-ylmethyl)sulfamide | S...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | N-(4-nitrophenyl)sulfamid...)
Affinity DataKd:  1.50E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | N-(4-nitrophenyl)sulfamid...)
Affinity DataKd:  1.00E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188393(Sulfamic acid 2,2-dimethyl-[1,3]dioxolan-4-ylmethy...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13055(amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,...)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13057(CHEMBL417656 | Cyclic Sulfate Analogue of Topirama...)
Affinity DataKd:  10nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188392(N-(2,2-dimethyl-1,3-dioxolan-4-ylmethyl)sulfamide ...)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(N-(4-methoxyphenyl)sulfamide | 4-methoxyphenylsulf...)
Affinity DataKd:  5.00E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163316(N-{[(3aR,5aS,8aS,8bS)-7,7-dimethyl-2,2-dioxidotetr...)
Affinity DataKd:  1.25E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKd:  4.55E+3nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50098106(CHEMBL24259 | phenyl sulfamate | Sulfamic acid phe...)
Affinity DataKi:  36nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | N-(4-nitrophenyl)sulfamid...)
Affinity DataKi:  892nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188393(Sulfamic acid 2,2-dimethyl-[1,3]dioxolan-4-ylmethy...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | N-(4-nitrophenyl)sulfamid...)
Affinity DataKi:  1.74E+3nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKi:  7.96E+3nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124170(CHEMBL168514 | N-phenylsulfamide | PHENYLSULFAMIDE)
Affinity DataKi:  8.02E+3nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(N-(4-methoxyphenyl)sulfamide | 4-methoxyphenylsulf...)
Affinity DataKi:  1.44E+4nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50124171(N-(4-methoxyphenyl)sulfamide | 4-methoxyphenylsulf...)
Affinity DataKi:  1.88E+4nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50188392(N-(2,2-dimethyl-1,3-dioxolan-4-ylmethyl)sulfamide ...)
Affinity DataKi:  4.08E+5nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed