Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50017836
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  230nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  710nMAssay Description:Inhibition of TCPTP I220A mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118762(2-oxalylamino-4,5,6,7-tetrahydrobenzo[b]thiophene-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of PTP1B V49A mutantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118762(2-oxalylamino-4,5,6,7-tetrahydrobenzo[b]thiophene-...)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed