Compile Data Set for Download or QSAR
Report error Found 89 Enz. Inhib. hit(s) with all data for entry = 50017797
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137196(6-Phenyl-thieno[3,2-d]pyrimidin-4-ylamine | CHEMBL...)
Affinity DataIC50: 970nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26098(3-amino-5-(thiophen-3-yl)thiophene-2-carboxamide |...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186653(amino-4-(4-carbamoyl-phenoxymethyl)-6-methyl-thien...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186637(3-(3-methyl-ureido)-5-phenyl-thiophene-2-carboxyli...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186655(2-amino-5-phenylthiophene-3-carboxamide | CHEMBL38...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186624(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbox...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186660(3-amino-6-butyl-4-methyl-thieno[2,3-b]pyridine-2-c...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186624(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbox...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186614(3-amino-5-(4-methoxyphenyl)thiophene-2-carboxamide...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186636(3-amino-6-tert-butyl-2-carbamoyl-thieno[2,3-b]pyri...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186624(3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbox...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186652(3-amino-6-isobutyl-4-methyl-thieno[2,3-b]pyridine-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186635(5-amino-2-benzthiophene-2-yl-oxazole-4-carboxylic ...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186645(5-amino-2-thiophen-3-yl-oxazole-4-carboxylic acid ...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186656(5-(4-fluoro-phenyl)-3-methylamino-thiophene-2-carb...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186639(4-(4-cyano-phenoxymethyl)-6-methyl-thieno[2,3-b]py...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186651(5-amino-2-(2-methyl-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186631(5-amino-2-(4-tert-butyl-phenyl)-oxazole-4-carboxyl...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186644(5-amino-2-(2-chloro-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186632(3-amino-5-(4-chlorophenyl)thiophene-2-carboxamide ...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186633(5-amino-2-(4-trifluoromethyl-phenyl)-oxazole-4-car...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186647(3-amino-6-methyl-4-phenoxymethyl-thieno[2,3-b]pyri...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186621(2-amino-quinoline-3-carboxylic acid amide | CHEMBL...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186617(5-phenyl-3-propionylamino-thiophene-2-carboxylic a...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186622(5-amino-2-(3-chloro-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186616(5-amino-2-phenyl-oxazole-4-carboxylic acid amide |...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186634(3-amino-benzo[b]thiophene-2-carboxylic acid amide ...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186628(5-amino-2-p-tolyl-oxazole-4-carboxylic acid amide ...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186650(3-amino-4-hydroxymethyl-6-methyl-thieno[2,3-b]pyri...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186654(4-(4-methoxy-phenoxymethyl)-6-methyl-thieno[2,3-b]...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186657(5-amino-2-(4-chloro-phenyl)-oxazole-4-carboxylic a...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186638(5-amino-2-(3-methoxy-phenyl)-oxazole-4-carboxylic ...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM27462(CHEMBL207940 | 2-amino-5-phenylbenzamide | Amino-s...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186619(3-amino-5-phenyl-thiophene-2-carboxylic acid amide...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186626(3-amino-2-carbamoyl-6-methyl-thieno[2,3-b]pyridine...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM114965(SMR000035281 | cid_661437 | CHEMBL381518 | MLS0000...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186623(5-amino-2-(4-methoxy-phenyl)-oxazole-4-carboxylic ...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186640(3-amino-5-methyl-thieno[2,3-b]pyridine-2-carboxyli...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186625(3-amino-thieno[2,3-b]pyridine-2-carboxylic acid am...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186659(3-dimethylamino-5-(4-fluoro-phenyl)-thiophene-2-ca...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186618(3-amino-5-(4-fluoro-phenyl)-thiophene-2-carboxylic...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of IKK alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 89 total ) | Next | Last >>
Jump to: