Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 2176
LigandPNGBDBM17659(pentanedioic acid analogue, (RS)-1 | 2-(phosphonom...)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM17775(3-(1-carboxy-4-sulfanylbutoxy)benzoic acid | Thiol...)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17762(3-[2-carboxy-2-(3-sulfanylpropyl)ethyl]benzoic aci...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17776(3-[(1-carboxy-4-sulfanylbutyl)sulfanyl]benzoic aci...)
Affinity DataIC50: 32nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17763(4-[2-carboxy-2-(3-sulfanylpropyl)ethyl]benzoic aci...)
Affinity DataIC50: 63nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17752(CHEMBL64901 | 2-({hydroxy[(2,3,4,5,6-pentafluoroph...)
Affinity DataIC50: 82nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17755(pentanedioic acid analogue, (RS)-3 | CHEMBL303352 ...)
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17777(3-[2-carboxy-2-(phosphonomethyl)ethyl]benzoic acid...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17767(3-[2-carboxy-2-(5-sulfanylpentyl)ethyl]benzoic aci...)
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17779(2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...)
Affinity DataIC50: 220nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17766(3-[2-carboxy-2-(4-sulfanylbutyl)ethyl]benzoic acid...)
Affinity DataIC50: 390nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17764(3-[2-carboxy-2-(sulfanylmethyl)ethyl]benzoic acid ...)
Affinity DataIC50: 440nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17771(3-[2-carbamoyl-2-(3-sulfanylpropyl)ethyl]benzoic a...)
Affinity DataIC50: 640nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17770(3-[3-methoxy-3-oxo-2-(3-sulfanylpropyl)propyl]benz...)
Affinity DataIC50: 730nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17765(3-[2-carboxy-2-(2-sulfanylethyl)ethyl]benzoic acid...)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17760(2-benzyl-5-sulfanylpentanoic acid | Thiol-Based In...)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17761(2-[2-carboxy-2-(3-sulfanylpropyl)ethyl]benzoic aci...)
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17774(2-[(3-cyanophenyl)methyl]-5-sulfanylpentanoic acid...)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17773(2-[(3-carbamoylphenyl)methyl]-5-sulfanylpentanoic ...)
Affinity DataIC50: 2.20E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17778(3-[2-carboxy-2-({hydroxy[(2,3,4,5,6-pentafluorophe...)
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17772(2-{[3-(methoxycarbonyl)phenyl]methyl}-5-sulfanylpe...)
Affinity DataIC50: 2.70E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17780(3-{2-carboxy-2-[(hydroxycarbamoyl)methyl]ethyl}ben...)
Affinity DataIC50: 1.50E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17782(2-[(3-carboxyphenyl)methyl]butanedioic acid | carb...)
Affinity DataIC50: 1.50E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17769(3-(2-carboxy-2-{3-[(triphenylmethyl)sulfanyl]propy...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17768(3-{2-carboxy-2-[3-(methylsulfanyl)propyl]ethyl}ben...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17781(CHEMBL65860 | butane-1,2,4-tricarboxylic acid | ca...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed