Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 50017787
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186457(1-(4-(5-(2-(4,6-dimethylpyridin-2-ylamino)thiazol-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186484(1-(4-(5-(2-(4,6-dimethylpyridin-2-ylamino)thiazol-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186478(1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186487(N-(5-(4-methoxy-2-methyl-5-(morpholine-4-carbonyl)...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186459(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186456(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-hydroxy-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186461(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186474(1-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50: 15nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186480(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186479(N-(5-(5-(1-(2-(dimethylamino)acetyl)piperazine-4-c...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186470(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186496(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186466(1-(4-(2-hydroxy-5-(2-(pyridin-2-ylamino)thiazol-5-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186472(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4-hydroxyp...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186467(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4-methoxyp...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186488(1-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186477(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186468(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-2,4-dimeth...)
Affinity DataIC50: 60nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186486(1-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50: 83nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186495(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4-aminophe...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50182833(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4,5-dimeth...)
Affinity DataIC50: 96nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186498(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4,5-dimeth...)
Affinity DataIC50: 210nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186497(N-(5-(4-acetamido-3-(1-acetylpiperazine-4-carbonyl...)
Affinity DataIC50: 250nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186476(N-(5-(5-(1-ethylpiperazine-4-carbonyl)-4-methoxy-2...)
Affinity DataIC50: 260nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186463(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4-methylph...)
Affinity DataIC50: 290nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186469(2-((5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy...)
Affinity DataIC50: 320nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186464(2-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50: 370nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186492(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-4-chloroph...)
Affinity DataIC50: 600nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186482(1-(4-(3-(2-(pyridin-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50: 690nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186458(N-(5-(3-(1-acetylpiperazine-4-carbonyl)benzyl)thia...)
Affinity DataIC50: 820nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186483(N-(5-((3-(1-acetylpiperazine-4-carbonyl)benzyloxy)...)
Affinity DataIC50: 930nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186473(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-2-methylph...)
Affinity DataIC50: 940nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186471(N-(5-(3-(1-acetylpiperazine-4-carbonyl)phenylthio)...)
Affinity DataIC50: 970nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50182839(N-(5-(3-(1-acetylpiperazine-4-carbonyl)benzylthio)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Insulin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186489(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-5-aminophe...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186475(N-(5-(((3-(1-acetylpiperazine-4-carbonyl)benzyl)(m...)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186494(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-2,3-dimeth...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of BtkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186491(1-(4-(3-(2-(pyrazin-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50: 6.06E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186455(1-(4-(3-(2-(thiazol-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50: 7.07E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of TxkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of TecMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186485(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-5-(trifluo...)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186465(N-(5-((3-(1-acetylpiperazine-4-carbonyl)benzylamin...)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of PKCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186462(N-(5-(3-(1-acetylpiperazine-4-carbonyl)-2-methylph...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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