Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 1104
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8888(3-(1H-Inden-2-yl)pyridine | indene 1 | US9271963, ...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8890(3-(5-Methoxy-1H-inden-2-yl)pyridine | indene 3)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8891(CHEMBL206351 | 3-(6-Methoxy-3,4-dihydronaphthalen-...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8893(3-(1-ethyl-3,4-dihydronaphthalen-2-yl)pyridine | 3...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 5nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8892(3-(1-methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8893(3-(1-ethyl-3,4-dihydronaphthalen-2-yl)pyridine | 3...)
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 40nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8901(3-(7-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)
Affinity DataIC50: 45nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8896(3-(4-Ethyl-3,4-dihydronaphthalen-2-yl)pyridine | D...)
Affinity DataIC50: 176nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 224nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8900(3-[(Z)-2-phenylethenyl]pyridine | 3-[(Z)-2-Phenylv...)
Affinity DataIC50: 288nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8898(1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole | Dihy...)
Affinity DataIC50: 334nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8899(1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidaz...)
Affinity DataIC50: 411nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8902(1-(1H-Inden-2-yl)-1H-imidazole | indene 12)
Affinity DataIC50: 448nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 503nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8891(CHEMBL206351 | 3-(6-Methoxy-3,4-dihydronaphthalen-...)
Affinity DataIC50: 578nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8898(1-(3,4-Dihydronaphthalen-2-yl)-1H-imidazole | Dihy...)
Affinity DataIC50: 639nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8900(3-[(Z)-2-phenylethenyl]pyridine | 3-[(Z)-2-Phenylv...)
Affinity DataIC50: 735nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8899(1-(6-Methoxy-3,4-dihydronaphthalen-2-yl)-1H-imidaz...)
Affinity DataIC50: 763nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8891(CHEMBL206351 | 3-(6-Methoxy-3,4-dihydronaphthalen-...)
Affinity DataIC50: 814nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8892(3-(1-methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 1.09E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8892(3-(1-methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 1.27E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 1.29E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8893(3-(1-ethyl-3,4-dihydronaphthalen-2-yl)pyridine | 3...)
Affinity DataIC50: 1.51E+3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8896(3-(4-Ethyl-3,4-dihydronaphthalen-2-yl)pyridine | D...)
Affinity DataIC50: 1.62E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)
Affinity DataIC50: 1.73E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 1.79E+3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8893(3-(1-ethyl-3,4-dihydronaphthalen-2-yl)pyridine | 3...)
Affinity DataIC50: 2.12E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8888(3-(1H-Inden-2-yl)pyridine | indene 1 | US9271963, ...)
Affinity DataIC50: 2.39E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8897(4-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)
Affinity DataIC50: 2.53E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8897(4-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)
Affinity DataIC50: 2.83E+3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 3.55E+3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)
Affinity DataIC50: 4.07E+3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8890(3-(5-Methoxy-1H-inden-2-yl)pyridine | indene 3)
Affinity DataIC50: 5.68E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8892(3-(1-methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)
Affinity DataIC50: 6.05E+3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8890(3-(5-Methoxy-1H-inden-2-yl)pyridine | indene 3)
Affinity DataIC50: 3.60E+4nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8888(3-(1H-Inden-2-yl)pyridine | indene 1 | US9271963, ...)
Affinity DataIC50: 3.60E+4nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8891(CHEMBL206351 | 3-(6-Methoxy-3,4-dihydronaphthalen-...)
Affinity DataKi:  1.30nM IC50: 2nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8890(3-(5-Methoxy-1H-inden-2-yl)pyridine | indene 3)
Affinity DataKi:  2.60nM IC50: 4nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)
Affinity DataKi:  4.60nM IC50: 7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8888(3-(1H-Inden-2-yl)pyridine | indene 1 | US9271963, ...)
Affinity DataKi:  8.40nM IC50: 13nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed