Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 1977
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM13531(4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15744(1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15749([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-{3-[2...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15743(1-(2,4-difluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15745(1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yloxy)phen...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15750([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(3...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15740(1-(4-fluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]carb...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15748(1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)p...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15746(2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15741([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-(4-py...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15718((5-Amino-1-O-tolyl-1H-pyrazol-4-yl)phenylmethanone...)
Affinity DataIC50: 1.08E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15720(4-benzoyl-1-(4-fluorophenyl)-1H-pyrazol-5-amine | ...)
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15753(5-Amino-1-(4-fluorophenyl)-4-[3-{2(R), 3-dihydroxy...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15747(2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15725(5-Amino-1-(4-fluorophenyl)-4-[3-(2-morpholin-4-yle...)
Affinity DataIC50: 1.27E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15742(1-(4-fluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]carb...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15734(1-(4-fluorophenyl)-4-({3-[3-(piperidin-1-yl)prop-1...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15728(1-(4-fluorophenyl)-4-({3-[2-(4-methylpiperazin-1-y...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15735(5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(3-...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15737(1-(4-fluorophenyl)-4-({3-[3-(morpholin-4-yl)propyl...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15739([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2...)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15726(1-(4-fluorophenyl)-4-{[3-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15732([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(3...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15714(4-benzoyl-1-phenyl-1H-pyrazol-5-amine | (5-Amino-1...)
Affinity DataIC50: 2.30E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15727(5-amino-4-[3-(2-aminoethyl)benzoyl]-1-(4-fluorophe...)
Affinity DataIC50: 2.44E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15733([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-{3-[3...)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15722(4-benzoyl-1-(2-fluorophenyl)-1H-pyrazol-5-amine | ...)
Affinity DataIC50: 2.86E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15736([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[4-(3...)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15751(1-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15731(3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15729(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]car...)
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15721(4-benzoyl-1-(3-fluorophenyl)-1H-pyrazol-5-amine | ...)
Affinity DataIC50: 6.70E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15723(4-benzoyl-1-(4-methoxyphenyl)-1H-pyrazol-5-amine |...)
Affinity DataIC50: 7.06E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15724(4-benzoyl-1-(2-methoxyphenyl)-1H-pyrazol-5-amine |...)
Affinity DataIC50: 8.38E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15730(4-[5-Amino-1-(4-fluorophenyl)-1H-pyrazole-4-carbon...)
Affinity DataIC50: 8.38E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15752([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(1...)
Affinity DataIC50: 9.54E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15738([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[4-(3...)
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15717((5-Amino-1-phenyl-1H-pyrazol-4-yl)phenylmethanone ...)
Affinity DataIC50: 5.10E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15719([5-Amino-1-(3-nitrophenyl)-1H-pyrazol-4-yl]phenylm...)
Affinity DataIC50: 6.42E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15716(4-benzoyl-3-methyl-1-phenyl-1H-pyrazol-5-ol | (5-H...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15715(4-benzoyl-1-phenyl-1H-pyrazole-5-carbonitrile | 4-...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed