Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50037698
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182198(N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({5-[(E)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182194(CHEMBL206418 | {(R)-2-[(S)-2-(4-carbamimidoyl-benz...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182196(((R)-2-{(S)-5-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182189({(R)-2-[(S)-2-(4-carbamimidoyl-benzylcarbamoyl)-py...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182210(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182197(((R)-2-{(S)-5-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182208(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 14.8nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182190(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 16nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182207([(R)-1-({(S)-1-[(6-carbamimidoyl-pyridin-3-ylmethy...)
Affinity DataIC50: 20.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182193(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 31.9nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182187(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 44.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182191(N-[(1R)-2-[(1-{[({6-[AMINO(IMINO)METHYL]PYRIDIN-3-...)
Affinity DataIC50: 47.3nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182204(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 56.3nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182211(((R)-2-{(R)-4-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 58.4nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50: 69.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182206(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 71.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182188(((R)-1-{(S)-1-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 76.8nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182205(((R)-1-{1-[(6-carbamimidoyl-pyridin-3-ylmethyl)-ca...)
Affinity DataIC50: 103nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182200(((R)-2-{(S)-4-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 288nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182203(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 290nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182192(((R)-1-{1-[(6-carbamimidoyl-pyridin-3-ylmethyl)-ca...)
Affinity DataIC50: 581nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182209(((R)-1-{1-[(6-carbamimidoyl-pyridin-3-ylmethyl)-ca...)
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50182202(((R)-1-{(R)-1-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed