Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50017438
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  10nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182160(4-[7-bromo-1-(2,6-dichloro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  20nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182171(4-(1-benzyl-7-bromo-1H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  30nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182170(4-[7-bromo-1-(2-fluoro-5-nitro-benzyl)-1H-benzoimi...)
Affinity DataKi:  30nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182159(4-[7-bromo-1-(2,6-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  40nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182176(4-[7-bromo-1-(3-methyl-but-2-enyl)-1H-benzoimidazo...)
Affinity DataKi:  50nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182185(4-(1-allyl-7-bromo-1H-benzoimidazole-5-sulfonyl)-5...)
Affinity DataKi:  70nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182173(4-[7-chloro-1-(2,6-difluoro-benzyl)-1H-benzoimidaz...)
Affinity DataKi:  100nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182183(4-[7-chloro-3-(2,6-difluoro-benzyl)-3H-benzoimidaz...)
Affinity DataKi:  100nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182164(4-[7-bromo-3-(2,6-dichloro-benzyl)-3H-benzoimidazo...)
Affinity DataKi:  160nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182181(4-[7-bromo-3-(2,6-difluoro-benzyl)-3H-benzoimidazo...)
Affinity DataKi:  170nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182174(4-[7-bromo-3-(2-fluoro-5-nitro-benzyl)-3H-benzoimi...)
Affinity DataKi:  170nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182180(4-(7-bromo-3-phenyl-3H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  180nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182153(4-[7-bromo-3-(3-methyl-but-2-enyl)-3H-benzoimidazo...)
Affinity DataKi:  200nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182182(4-(3-allyl-7-bromo-3H-benzoimidazole-5-sulfonyl)-5...)
Affinity DataKi:  210nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182169(4-[7-bromo-3-(2,5-difluoro-benzyl)-3H-benzoimidazo...)
Affinity DataKi:  240nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182186(4-(7-bromo-1-phenyl-1H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  310nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182161(4-(7-bromo-3-methyl-3H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  330nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182156(4-[7-bromo-1-((S)-1-phenyl-ethyl)-1H-benzoimidazol...)
Affinity DataKi:  330nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182172(4-[7-bromo-1-((R)-1-phenyl-ethyl)-1H-benzoimidazol...)
Affinity DataKi:  380nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182168(4-(7-bromo-3H-benzo[d]imidazol-5-ylsulfonyl)-5-(me...)
Affinity DataKi:  400nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182165(4-(7-bromo-1-methyl-1H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  400nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182178(4-(1-benzyl-1H-benzoimidazole-5-sulfonyl)-5-methyl...)
Affinity DataKi:  400nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182179(4-(3-benzyl-7-bromo-3H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  400nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182167(5-methylsulfanyl-4-(naphthalene-2-sulfonyl)-thioph...)
Affinity DataKi:  410nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182177(4-(3-benzyl-3H-benzoimidazole-5-sulfonyl)-5-methyl...)
Affinity DataKi:  420nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182155(5-methylsulfanyl-4-(1-pyridin-2-ylmethyl-1H-benzoi...)
Affinity DataKi:  580nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182166(4-benzenesulfonyl-5-methylsulfanyl-thiophene-2-car...)
Affinity DataKi:  750nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182184(4-(2-methyl-furan-3-sulfonyl)-5-methylsulfanyl-thi...)
Affinity DataKi:  1.79E+3nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182175(4-(1-methyl-1H-imidazole-2-sulfonyl)-5-methylsulfa...)
Affinity DataKi:  1.88E+3nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182158(5-methylsulfanyl-4-phenylmethanesulfonyl-thiophene...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182162(5-methylsulfanyl-4-(thiophene-2-sulfonyl)-thiophen...)
Affinity DataKi:  2.24E+3nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182157(5-methylsulfanyl-4-(pyridine-2-sulfonyl)-thiophene...)
Affinity DataKi:  2.29E+3nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1s subcomponent(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182154(4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-ca...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed