Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50017430
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182067(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182065(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182072(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 97nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182073(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182078(N-(4-diethylamino-1-methyl-butyl)-N'-{2-[2-(3,5-di...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182083(N-[4-(benzyl-methyl-amino)-butyl]-N'-{2-[2-(5-brom...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182064(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182068(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-thiophen...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182077(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182076(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 390nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182081(N-[2-(5-bromo-2-methoxy-benzyloxy)-3-fluoro-benzoy...)
Affinity DataIC50: 530nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182062(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 650nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182074(N-{2-[2-(5-bromo-2-chloro-phenyl)-ethyl]-3-fluoro-...)
Affinity DataIC50: 660nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182080(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 670nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182060(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182070(N-(4-diethylamino-1-methyl-butyl)-N'-[3-fluoro-2-(...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182063(N-(4-diethylamino-1-methyl-butyl)-N'-[3-fluoro-2-(...)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182069(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Affinity DataIC50: 2.58E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182061(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182058(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182075(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 8.50E+3nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182071(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataIC50: 1.70E+4nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182059(N-{2-[2-(2-chloro-phenyl)-ethyl]-3-fluoro-benzoyl}...)
Affinity DataIC50: 3.30E+4nMAssay Description:Antagonist activity against MC4R by cAMP functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182065(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182064(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182072(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182077(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182073(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182083(N-[4-(benzyl-methyl-amino)-butyl]-N'-{2-[2-(5-brom...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182068(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-thiophen...)
Affinity DataKi:  11nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182067(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  13nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182078(N-(4-diethylamino-1-methyl-butyl)-N'-{2-[2-(3,5-di...)
Affinity DataKi:  14nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182076(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  21nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182062(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  26nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182060(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  57nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182080(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  64nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182058(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  80nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182070(N-(4-diethylamino-1-methyl-butyl)-N'-[3-fluoro-2-(...)
Affinity DataKi:  89nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182074(N-{2-[2-(5-bromo-2-chloro-phenyl)-ethyl]-3-fluoro-...)
Affinity DataKi:  110nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182061(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  190nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182063(N-(4-diethylamino-1-methyl-butyl)-N'-[3-fluoro-2-(...)
Affinity DataKi:  690nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182069(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Affinity DataKi:  700nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182075(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  770nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182085(2-(2-(5-bromo-2-methoxyphenethyl)-3-chlorophenyl)-...)
Affinity DataKi:  840nMAssay Description:Binding affinity to hERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182081(N-[2-(5-bromo-2-methoxy-benzyloxy)-3-fluoro-benzoy...)
Affinity DataKi:  900nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182066(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  920nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182071(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182079(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182069(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Affinity DataKi:  3.15E+3nMAssay Description:Binding affinity to hERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182082(N-{2-[2-(5-bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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