Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50017374
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181249(5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181245(3-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181261(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-bromobenzyl)-5...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181255(4-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181252(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-(methylthiomet...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181239(3-(3-(1H-imidazol-1-yl)propyl)-1-(3-chlorobenzyl)-...)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181248(N-(4-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181258(3-(3-(1H-imidazol-1-yl)propyl)-1-(3-bromobenzyl)-5...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181246(N-(2-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181240(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-(methylthio)be...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181235(3-(3-(1H-imidazol-1-yl)propyl)-1-(3-phenoxybenzyl)...)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181247(5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181242(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-phenoxybenzyl)...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181259((2S)-2-(2-(3-(3-(1H-imidazol-5-yl)propyl)-5-methyl...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181260(4-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181233(ethyl 2-(3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5...)
Affinity DataIC50: 1nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181236(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-(methylsulfony...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181251(N-(3-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181254(2-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181243(3-(3-(1H-imidazol-1-yl)propyl)-1-(3-(trifluorometh...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181257(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-(aminomethyl)b...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181250(ethyl 2-(5-methyl-3-(3-(1-methyl-1H-imidazol-5-yl)...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181253(ethyl 2-(3-(3-(1H-imidazol-4-yl)propyl)-5-methyl-5...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181232((2S)-2-(2-(3-(2-(1H-imidazol-5-yl)ethyl)-5-methyl-...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181256(3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(naphtha...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181238(3-(3-(1H-imidazol-5-yl)propyl)-5-methyl-5-(naphtha...)
Affinity DataIC50: 40nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181244((2S)-2-(2-(3-((1H-imidazol-5-yl)methyl)-5-methyl-5...)
Affinity DataIC50: 61nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181234((2S)-methyl 2-(2-(3-(3-(1H-imidazol-5-yl)propyl)-5...)
Affinity DataIC50: 500nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181241((2S)-methyl 2-(2-(3-(2-(1H-imidazol-5-yl)ethyl)-5-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181237((2S)-methyl 2-(2-(3-((1H-imidazol-5-yl)methyl)-5-m...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed