Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 1201
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9932((2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-2-{[(2-met...)
Affinity DataKi:  15nM ΔG°:  -45.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9939(2-methylpropyl N-[(S)-cyclohexyl({[(1S)-2-cyclopro...)
Affinity DataKi:  50nM ΔG°:  -42.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9938(depeptidized alpha-ketoamide inhibitor 34)
Affinity DataKi:  60nM ΔG°:  -41.9kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9937((2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-N-methyl-2...)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9936((2S)-2-{2-[3-({N'-[(2S)-2-cyclohexyl-2-{[(2-methyl...)
Affinity DataKi:  230nM ΔG°:  -38.5kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9935((2S)-2-{2-[3-({[(3S)-3-cyclohexyl-3-{[(2-methylpro...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9934((2S)-2-{2-[3-({[(2S,3S)-3-cyclohexyl-2-hydroxy-3-{...)
Affinity DataKi:  1.00E+4nM ΔG°:  -29.0kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9933((2S)-2-(2-{3-[(2S)-2-[(3S,4S)-4-cyclohexyl-3-hydro...)
Affinity DataKi:  4.20E+4nM ΔG°:  -25.4kJ/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2006
Entry Details Article
PubMed