Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 2258
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 84nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18720(2-chloro-3-{2,2-dimethyl-4-[(prop-2-en-1-ylsulfany...)
Affinity DataIC50: 129nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18719(dihydroquinoline-based ligand, 35 | 6-(5-fluoro-2-...)
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18713(dihydroquinoline-based ligand, 36 | 6-(2-methoxyph...)
Affinity DataIC50: 194nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18722(2-chloro-3-(2,2-dimethyl-4-{[(2-phenylethyl)sulfan...)
Affinity DataIC50: 220nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18709(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-methylbuty...)
Affinity DataIC50: 303nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18705(dihydroquinoline-based ligand, 13 | 6-(2-methoxyph...)
Affinity DataIC50: 360nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18717(6-(2-fluorophenyl)-2,2-dimethyl-4-[(prop-2-en-1-yl...)
Affinity DataIC50: 360nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18708(4-[(cyclohexylsulfanyl)methyl]-6-(2-methoxyphenyl)...)
Affinity DataIC50: 371nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18705(dihydroquinoline-based ligand, 13 | 6-(2-methoxyph...)
Affinity DataIC50: 460nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18718(6-(3-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Affinity DataIC50: 460nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18707(4-[(cyclopentylsulfanyl)methyl]-6-(2-methoxyphenyl...)
Affinity DataIC50: 548nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18715(1-({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroq...)
Affinity DataIC50: 620nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18712(4-[(benzylsulfanyl)methyl]-6-(2-methoxyphenyl)-2,2...)
Affinity DataIC50: 660nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18710(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(3-methylbuty...)
Affinity DataIC50: 703nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18714(4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...)
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18711(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(phenylsulfany...)
Affinity DataIC50: 804nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18720(2-chloro-3-{2,2-dimethyl-4-[(prop-2-en-1-ylsulfany...)
Affinity DataIC50: 960nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18718(6-(3-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18706(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(propylsulfany...)
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18719(dihydroquinoline-based ligand, 35 | 6-(5-fluoro-2-...)
Affinity DataIC50: 1.40E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18722(2-chloro-3-(2,2-dimethyl-4-{[(2-phenylethyl)sulfan...)
Affinity DataIC50: 1.40E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18706(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(propylsulfany...)
Affinity DataIC50: 1.60E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18721(dihydroquinoline-based ligand, 37 | 6-(5-fluoro-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18716(6-(2-methoxyphenyl)-2,2,4-trimethyl-1,2-dihydroqui...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18714(4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18713(dihydroquinoline-based ligand, 36 | 6-(2-methoxyph...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18702({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquin...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18711(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(phenylsulfany...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18710(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(3-methylbuty...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18709(6-(2-methoxyphenyl)-2,2-dimethyl-4-{[(2-methylbuty...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18708(4-[(cyclohexylsulfanyl)methyl]-6-(2-methoxyphenyl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18707(4-[(cyclopentylsulfanyl)methyl]-6-(2-methoxyphenyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18704(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18702({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquin...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18717(6-(2-fluorophenyl)-2,2-dimethyl-4-[(prop-2-en-1-yl...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18716(6-(2-methoxyphenyl)-2,2,4-trimethyl-1,2-dihydroqui...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18715(1-({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroq...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18712(4-[(benzylsulfanyl)methyl]-6-(2-methoxyphenyl)-2,2...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM18704(6-(2-methoxyphenyl)-2,2-dimethyl-4-[(prop-2-en-1-y...)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed