Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50017247
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179567((+)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-hydroxyquinoli...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179569((3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-methoxyquinolin-2-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179569((3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-methoxyquinolin-2-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179581((+)-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179587((+)-N-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179578((+)-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179562((+)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-aminoquinolin-...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179577((+)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(5,6-dimethoxyqui...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179571((+)-(3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(6-(thio...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179574((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(quinolin-2-...)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179574((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(quinolin-2-...)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179585((+)-N-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 68nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179565((+)-N-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179586((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-ethoxyquinol...)
Affinity DataIC50: 125nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179588((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(7-met...)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179566((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-chloroquinol...)
Affinity DataIC50: 155nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179576((+)-N-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 219nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179575((+/-)-tert-butyl 2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-...)
Affinity DataIC50: 275nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179564((+)-N-cyclopropyl-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)...)
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179579((+)-(3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(6-(thio...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179584((+)-(3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(6-(3-(t...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179582((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(8-met...)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179573((+)-(3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(6-(2-mo...)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179590((+)-2-methyl-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-me...)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179589((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(8-methoxyquino...)
Affinity DataIC50: 700nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179563((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-fluoroquinol...)
Affinity DataIC50: 730nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179570((+/-)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(5-chloro-6-met...)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179568((+)-2-methyl-2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-me...)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179580((+)2-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-oxo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179583((+)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-(benzyloxy)qui...)
Affinity DataIC50: 1.25E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179572((+)-N-(2-(2-((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-1-ox...)
Affinity DataIC50: 2.15E+3nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed