Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50044029
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataKd:  8nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM11834(3-{2-[(dimethylamino)methyl]-1H,2H,3H,4H-pyrido[1,...)
Affinity DataKd:  250nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKd:  25nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM2695(Ro 31-7549 | 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4...)
Affinity DataKd:  12nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM11835(Cancer Res 676916 Compound K00135 | CHEMBL200528 |...)
Affinity DataKd:  25nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataKd:  10nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM11833(3-[2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...)
Affinity DataKd:  72nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM2583(bis-indolylmaleimide deriv. 8a | 3,4-bis(1H-indol-...)
Affinity DataKd:  27nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Oxford University

Curated by ChEMBL
LigandPNGBDBM11835(Cancer Res 676916 Compound K00135 | CHEMBL200528 |...)
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed