Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50017127
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-methyl-8-a...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]CFT from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-methyl-8-a...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-methyl-8-a...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]dopamine from human NET expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-methyl-8-a...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]5HT from human SERT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177767(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]CFT from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177766(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]CFT from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177769([1-(3-{2-[3-(3,4-Dichloro-phenyl)-2-methoxycarbony...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]CFT from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177767(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177766(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177766(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  177nMAssay Description:Displacement of [3H]dopamine from human NET expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177767(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]dopamine from human NET expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177769([1-(3-{2-[3-(3,4-Dichloro-phenyl)-2-methoxycarbony...)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]5HT from human SERT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177769([1-(3-{2-[3-(3,4-Dichloro-phenyl)-2-methoxycarbony...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177769([1-(3-{2-[3-(3,4-Dichloro-phenyl)-2-methoxycarbony...)
Affinity DataKi:  308nMAssay Description:Displacement of [3H]dopamine from human NET expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177767(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]5HT from human SERT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177768(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  436nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177768(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  627nMAssay Description:Displacement of [3H]dopamine from human NET expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177768(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  705nMAssay Description:Displacement of [3H]5HT from human SERT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50177766(2-(3-sec-Butylimino-6-diethylamino-3H-xanthen-9-yl...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]5HT from human SERT expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed