Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with all data for entry = 50017118
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177695(3-(1-heptyl-trans-4,5-dimethyl-2-alpha-propylpiper...)
Affinity DataIC50: 9nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177701(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-propylpi...)
Affinity DataIC50: 15nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177702(3-(trans-4,5-dimethyl-1-(3-phenylpropyl)-2-alpha-p...)
Affinity DataIC50: 16nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177692(3-(1-hexyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataIC50: 39nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataIC50: 50nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177698(3-(2-alpha-ethyl-trans-4,5-dimethyl-1-phenethylpip...)
Affinity DataIC50: 90nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177688(3-(1-ethyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataIC50: 100nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177683(3-(2-alpha-butyl-trans-4,5-dimethyl-1-phenethylpip...)
Affinity DataIC50: 120nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177681(N-(2-(4-(3-hydroxyphenyl)-trans-4,5-dimethyl-1-phe...)
Affinity DataIC50: 130nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177685(N-(2-(4-(3-hydroxyphenyl)-trans-4,5-dimethyl-1-phe...)
Affinity DataIC50: 130nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177687(3-(1-benzyl-4,5-trans-dimethyl-2-alpha-propylpiper...)
Affinity DataIC50: 170nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177686(3-(1-methyl-4,5-trans-dimethyl-2-alpha-propylpiper...)
Affinity DataIC50: 170nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177691(3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperi...)
Affinity DataIC50: 210nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177690(3-(trans-4,5-dimethyl-1-pentyl-2-alpha-propylpiper...)
Affinity DataIC50: 210nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177684(3-(2-alpha-benzyl-trans-4,5-dimethyl-1-phenethylpi...)
Affinity DataIC50: 280nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177694(3-(1-butyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataIC50: 290nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177693(3-(trans-4,5-dimethyl-1,2(alpha)-dipropylpiperidin...)
Affinity DataIC50: 320nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177682(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-(3-pheny...)
Affinity DataIC50: 360nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177697(3-(2-alpha-(2-aminoethyl)-trans-4,5-dimethyl-1-phe...)
Affinity DataIC50: 390nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177700(3-(2-alpha-isopropyl-trans-4,5-dimethyl-1-phenethy...)
Affinity DataIC50: 620nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177689(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-phenylpi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177699(3-(trans-4,5-dimethyl-2-alpha-propylpiperidin-4-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177680(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-(2-(pyrr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of loperamide-stimulated [35S]GTPgammaS binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177695(3-(1-heptyl-trans-4,5-dimethyl-2-alpha-propylpiper...)
Affinity DataKi:  13nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataKi:  15nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177702(3-(trans-4,5-dimethyl-1-(3-phenylpropyl)-2-alpha-p...)
Affinity DataKi:  19nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177701(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-propylpi...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50045767((+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydr...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177692(3-(1-hexyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177695(3-(1-heptyl-trans-4,5-dimethyl-2-alpha-propylpiper...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177685(N-(2-(4-(3-hydroxyphenyl)-trans-4,5-dimethyl-1-phe...)
Affinity DataKi:  59nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177702(3-(trans-4,5-dimethyl-1-(3-phenylpropyl)-2-alpha-p...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177698(3-(2-alpha-ethyl-trans-4,5-dimethyl-1-phenethylpip...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177695(3-(1-heptyl-trans-4,5-dimethyl-2-alpha-propylpiper...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177696(3-(2(alpha),4,5(trans)-trimethyl-1-phenethylpiperi...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177701(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-propylpi...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177683(3-(2-alpha-butyl-trans-4,5-dimethyl-1-phenethylpip...)
Affinity DataKi:  110nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177701(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-propylpi...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177692(3-(1-hexyl-trans-4,5-dimethyl-2-alpha-propylpiperi...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177691(3-(trans-4,5-dimethyl-1,2(alpha)-diphenethylpiperi...)
Affinity DataKi:  160nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177702(3-(trans-4,5-dimethyl-1-(3-phenylpropyl)-2-alpha-p...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177681(N-(2-(4-(3-hydroxyphenyl)-trans-4,5-dimethyl-1-phe...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177685(N-(2-(4-(3-hydroxyphenyl)-trans-4,5-dimethyl-1-phe...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177683(3-(2-alpha-butyl-trans-4,5-dimethyl-1-phenethylpip...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177686(3-(1-methyl-4,5-trans-dimethyl-2-alpha-propylpiper...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50177682(3-(trans-4,5-dimethyl-1-phenethyl-2-alpha-(3-pheny...)
Affinity DataKi:  230nMAssay Description:Inhibition of loperamide-stimulated [35S]GTP-gamma-S binding to membranes containing mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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