Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 2390
TargetEstrogen receptor(Human)
Eli Lilly

LigandPNGBDBM19964(6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.200nM ΔG°:  -54.8kJ/mole EC50:  1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Eli Lilly

LigandPNGBDBM19967(6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...)
Affinity DataKi:  0.25nM ΔG°:  -54.3kJ/mole EC50:  3.18nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

LigandPNGBDBM19967(6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...)
Affinity DataKi:  0.300nM ΔG°:  -53.8kJ/mole EC50:  3.18nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Eli Lilly

LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  0.370nM ΔG°:  -53.3kJ/mole EC50:  4.32nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Eli Lilly

LigandPNGBDBM19966(CHEMBL243789 | LY 2066948 | 6-(4-methylsulfonylphe...)
Affinity DataKi:  0.510nM ΔG°:  -52.5kJ/mole EC50:  10.7nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

LigandPNGBDBM19964(6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.700nM ΔG°:  -51.7kJ/mole EC50:  1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Eli Lilly

LigandPNGBDBM19965(6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-...)
Affinity DataKi:  1.15nM ΔG°:  -50.5kJ/mole EC50:  4.78nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

LigandPNGBDBM19966(CHEMBL243789 | LY 2066948 | 6-(4-methylsulfonylphe...)
Affinity DataKi:  1.36nM ΔG°:  -50.1kJ/mole EC50:  10.7nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataKi:  2.74nM ΔG°:  -48.4kJ/mole EC50:  4.32nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

LigandPNGBDBM19965(6-(4-methanesulfonylphenyl)-5-({4-[2-(piperidin-1-...)
Affinity DataKi:  24.1nM ΔG°:  -43.0kJ/mole EC50:  4.78nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed