Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50016953
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175734(4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-...)
Affinity DataEC50:  98nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175719(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataEC50:  14nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175741(4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...)
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175725(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataEC50:  26nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175731(4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpipe...)
Affinity DataEC50:  117nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175740(4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-...)
Affinity DataEC50:  436nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175737(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-methoxyphenyl)-...)
Affinity DataEC50:  117nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175723(4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-dipheny...)
Affinity DataEC50:  776nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175717(4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidi...)
Affinity DataEC50:  832nMAssay Description:Agonist potency assessed by [35S]GTP-gammaS binding assay in C6 Glioma cells expressing cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175717(4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidi...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175723(4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-dipheny...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175719(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175738(4-(1-benzyl-1H-imidazol-2-yl)-N-(3-fluorophenyl)-4...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175733(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175737(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-methoxyphenyl)-...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175731(4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpipe...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175722(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175727(N,4-diphenyl-4-(1-(1-phenylethyl)-1H-imidazol-2-yl...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175728(4-(1-benzyl-1H-imidazol-2-yl)-N-(4-methoxyphenyl)-...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175740(4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175739(4-(1-benzyl-1H-imidazol-2-yl)-1-(methylsulfonyl)-4...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175730(N,4-diphenyl-4-(1-(pyridin-2-ylmethyl)-1H-imidazol...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175735(4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175725(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175734(4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175741(4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175729(4-(1-benzyl-1H-imidazol-2-yl)-N-(4-fluorophenyl)-4...)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175720(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidine-1...)
Affinity DataKi:  99nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175721(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidine-1...)
Affinity DataKi:  106nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175735(4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175741(4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175724(4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Affinity DataKi:  128nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175722(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  138nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175729(4-(1-benzyl-1H-imidazol-2-yl)-N-(4-fluorophenyl)-4...)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175740(4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-...)
Affinity DataKi:  152nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175718((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)
Affinity DataKi:  161nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175732(4-(1-(4-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175716(4-(1-(3-methoxybenzyl)-1H-imidazol-2-yl)-N,4-diphe...)
Affinity DataKi:  217nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175722(2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)
Affinity DataKi:  235nMAssay Description:Displacement of [3H]DAMGO from cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175731(4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpipe...)
Affinity DataKi:  242nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175733(4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...)
Affinity DataKi:  318nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175720(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidine-1...)
Affinity DataKi:  334nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175717(4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidi...)
Affinity DataKi:  346nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175723(4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-dipheny...)
Affinity DataKi:  397nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175735(4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...)
Affinity DataKi:  428nMAssay Description:Displacement of [3H]DAMGO from cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175726(4-(1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carb...)
Affinity DataKi: >465nMAssay Description:Displacement of [3H]DPDPE from cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175728(4-(1-benzyl-1H-imidazol-2-yl)-N-(4-methoxyphenyl)-...)
Affinity DataKi: >465nMAssay Description:Displacement of [3H]DAMGO from cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175727(N,4-diphenyl-4-(1-(1-phenylethyl)-1H-imidazol-2-yl...)
Affinity DataKi: >465nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175726(4-(1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carb...)
Affinity DataKi: >465nMAssay Description:Displacement of [3H]DAMGO from cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50175741(4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...)
Affinity DataKi: >465nMAssay Description:Displacement of [3H]DAMGO from cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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