Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 2014
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM16097(2-[methyl(naphthalene-2-)amido]benzoic acid | 2-[m...)
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM16098(2-(naphthalene-2-amido)benzoic acid | 2-[(naphthal...)
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16093(2-[methyl(4-phenylbenzene)amido]benzoic acid | 2-[...)
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16095(2-[(6-bromonaphthalene-2-)(methyl)amido]benzoic ac...)
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16097(2-[methyl(naphthalene-2-)amido]benzoic acid | 2-[m...)
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16094(2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid | 2-[...)
Affinity DataKi:  700nM ΔG°:  -35.1kJ/mole IC50: 5.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16096(2-{[(6-bromonaphthalen-2-yl)carbonyl]amino}benzoic...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/mole IC50: 8.40E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
LigandPNGBDBM16098(2-(naphthalene-2-amido)benzoic acid | 2-[(naphthal...)
Affinity DataKi:  1.80E+3nM ΔG°:  -32.8kJ/mole IC50: 1.38E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM16093(2-[methyl(4-phenylbenzene)amido]benzoic acid | 2-[...)
Affinity DataKi:  4.90E+3nM ΔG°:  -30.3kJ/mole IC50: 4.26E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM16095(2-[(6-bromonaphthalene-2-)(methyl)amido]benzoic ac...)
Affinity DataKi:  1.08E+4nM ΔG°:  -28.3kJ/mole IC50: 9.34E+4nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM16096(2-{[(6-bromonaphthalen-2-yl)carbonyl]amino}benzoic...)
Affinity DataKi:  1.64E+4nM ΔG°:  -27.3kJ/mole IC50: 1.43E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Leeds

LigandPNGBDBM16094(2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid | 2-[...)
Affinity DataKi:  1.77E+4nM ΔG°:  -27.1kJ/mole IC50: 1.54E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed