Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50016878
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174697(3-fluoro-N-[5-(7-methoxy-10,11-dihydro-5-oxa-2,4,1...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174698(4-fluoro-N-[5-(7-methoxy-10,11-dihydro-5-oxa-2,4,1...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174686(1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 450nMAssay Description:Inhibitory activity against FLT3 kinase in a HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174689(N-[5-(7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-tri...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174692(N-[5-(7-methoxy-10,11-dihydro-5-oxa-2,4,11-triaza-...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174701(1-(3-chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibe...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against FLT3 kinase in a HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174690(N-[5-(8-methoxy-10,11-dihydro-5-oxa-2,4,11-triaza-...)
Affinity DataIC50: 970nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174691(3-fluoro-N-[5-(8-methoxy-10,11-dihydro-5-oxa-2,4,1...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174694(N-[5-(7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-tri...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174700(N-[5-(7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-tri...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174695(N-[5-(10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174699(N-[5-(9-methoxy-10,11-dihydro-5-oxa-2,4,11-triaza-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174688(N-[5-(8-methoxy-10,11-dihydro-5-oxa-2,4,11-triaza-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174687(N-[5-(10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174693(N-[5-(7-diethylamino-10,11-dihydro-5-oxa-2,4,11-tr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174686(1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174686(1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against IRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174696(N-[5-(6-methoxy-10,11-dihydro-5-oxa-2,4,11-triaza-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174685(1-(1-chloro-10,11-dihydro-5-oxa-2,4,11-triaza-dibe...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibitory activity against FLT3 kinase in a HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed