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Found
173
Enz. Inhib. hit(s) with all data for entry = 5512
Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0300nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86187
(CAS_22189-31-7 | NSC_5454 | THIOTHIXENE)
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Affinity Data
Ki: 0.0300nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM84734
(CAS_129029-23-8 | NSC_71351 | Ocaperidone)
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Affinity Data
Ki: 0.100nM
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Date in BDB:
6/10/2012
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
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Ki: 0.100nM
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Date in BDB:
6/10/2012
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM81486
(NSC_4249 | CAS_1050-79-9 | MOPERONE)
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Ki: 0.100nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86722
(CAS_53772-85-3 | NSC_17012 | Flupenthixol, Beta | ...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM26948
(CHEMBL46516 | cid_3396 | FLUSPIRILENE | 8-[4,4-bis...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM26948
(CHEMBL46516 | cid_3396 | FLUSPIRILENE | 8-[4,4-bis...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM22872
(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM78434
(2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phen...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86723
(CAS_14759-06-9 | NSC_31765 | sulforidazine)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86187
(CAS_22189-31-7 | NSC_5454 | THIOTHIXENE)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM81493
(CAS_749-13-3 | TRIFLUORPERIDOL)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM81484
(BROMPERIDOL | CAS_2448 | NSC_2448 | Bromoperidol)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM22872
(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Ki: 0.200nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Copy SMILES
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Affinity Data
Ki: 0.200nM
More data for this Ligand-Target Pair
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Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86721
(CAS_51152-91-1 | NSC_37459 | BUTACLAMOL | US111478...)
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Affinity Data
Ki: 0.300nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 0.300nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Copy SMILES
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Affinity Data
Ki: 0.300nM
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Target Info
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86723
(CAS_14759-06-9 | NSC_31765 | sulforidazine)
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Affinity Data
Ki: 0.300nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50002012
((trans) 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethy...)
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Affinity Data
Ki: 0.300nM
More data for this Ligand-Target Pair
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CHEMBL
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Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Affinity Data
Ki: 0.300nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86187
(CAS_22189-31-7 | NSC_5454 | THIOTHIXENE)
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Ki: 0.300nM
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Date in BDB:
6/10/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86721
(CAS_51152-91-1 | NSC_37459 | BUTACLAMOL | US111478...)
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Affinity Data
Ki: 0.400nM
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PC cid
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Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Affinity Data
Ki: 0.400nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM84734
(CAS_129029-23-8 | NSC_71351 | Ocaperidone)
Copy SMILES
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Affinity Data
Ki: 0.400nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM81493
(CAS_749-13-3 | TRIFLUORPERIDOL)
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Ki: 0.400nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM26948
(CHEMBL46516 | cid_3396 | FLUSPIRILENE | 8-[4,4-bis...)
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Ki: 0.400nM
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Date in BDB:
6/10/2012
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Target
D(4) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM22872
(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
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Ki: 0.400nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86722
(CAS_53772-85-3 | NSC_17012 | Flupenthixol, Beta | ...)
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Ki: 0.5nM
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Affinity Data
Ki: 0.5nM
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Date in BDB:
6/10/2012
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50010637
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Ki: 0.5nM
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PC cid
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Date in BDB:
6/10/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86187
(CAS_22189-31-7 | NSC_5454 | THIOTHIXENE)
Copy SMILES
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Ki: 0.5nM
More data for this Ligand-Target Pair
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Date in BDB:
6/10/2012
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 0.600nM
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In Depth
Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 0.600nM
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PDB
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86722
(CAS_53772-85-3 | NSC_17012 | Flupenthixol, Beta | ...)
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Ki: 0.600nM
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Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 0.600nM
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PDB
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50002012
((trans) 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethy...)
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Ki: 0.600nM
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Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM81486
(NSC_4249 | CAS_1050-79-9 | MOPERONE)
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Ki: 0.700nM
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Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM22872
(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
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Ki: 0.700nM
More data for this Ligand-Target Pair
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ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50002012
((trans) 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethy...)
Copy SMILES
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Affinity Data
Ki: 0.700nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM84734
(CAS_129029-23-8 | NSC_71351 | Ocaperidone)
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Ki: 0.700nM
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Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
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PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM86723
(CAS_14759-06-9 | NSC_31765 | sulforidazine)
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Ki: 0.700nM
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PC sid
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.800nM
More data for this Ligand-Target Pair
Target Info
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Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
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Ki: 0.900nM
More data for this Ligand-Target Pair
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PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(3) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM22872
(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.900nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(2) dopamine receptor
(Human)
Acadia Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
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