Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50037609
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172608((4R,5R)-3,3-Dibutyl-7-dimethylamino-9-methoxy-5-(4...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370665(CHEMBL555024)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172631((3S,4R,5R)-3-Butyl-7-dimethylamino-3-ethyl-1,1-dio...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50140283((4R,5R)-3,3-Dibutyl-7-dimethylamino-5-(4-methoxy-p...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172617((4R,5R)-3,3-Dibutyl-7-dimethylamino-5-(4-fluoro-ph...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172641((4R,5R)-3,3-Dibutyl-7-dimethylamino-1,1-dioxo-5-ph...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172623((3S,4R,5R)-3-Butyl-3-ethyl-5-(4-fluoro-phenyl)-7-m...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172610((3S,4R,5R)-3-Butyl-3-ethyl-5-(4-fluoro-phenyl)-7-m...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172637((4R,5R)-3,3-Dibutyl-5-(4-fluoro-phenyl)-7-methyl-1...)
Affinity DataIC50: 46nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172632((4R,5R)-3,3-Dibutyl-5-(4-fluoro-phenyl)-7-methoxy-...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172636((4R,5R)-7-Amino-3,3-dibutyl-1,1-dioxo-5-phenyl-2,3...)
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172633((3S,4R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxo-5-p...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172612((3S,4R,5R)-3-Butyl-3-ethyl-5-(4-fluoro-phenyl)-1,1...)
Affinity DataIC50: 59nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172609((3S,4R,5R)-7-Amino-3-butyl-3-ethyl-1,1-dioxo-5-phe...)
Affinity DataIC50: 68nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172603((3S,4R,5R)-7-Bromo-3-butyl-3-ethyl-5-(3-methoxy-ph...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172615(((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1-dioxo-5-...)
Affinity DataIC50: 83nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172640(N-((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1-dioxo-...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172629((3S,4R,5R)-3-Butyl-3-ethyl-1,1-dioxo-5-phenyl-2,3,...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172625((3S,4R,5R)-3-Butyl-3-ethyl-8-methoxy-1,1-dioxo-5-p...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172611((4R,5R)-3,3-Dibutyl-8-dimethylamino-1,1-dioxo-5-ph...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172618((3S,4R,5R)-3-Butyl-3-ethyl-5-(3-methoxy-phenyl)-1,...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172634((4R,5R)-3,3-Dibutyl-9-dimethylamino-5-(4-fluoro-ph...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172619((4R,5R)-3,3-Dibutyl-9-fluoro-5-(4-fluoro-phenyl)-1...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172604((4R,5R)-3,3-Dibutyl-8-methoxy-1,1-dioxo-5-phenyl-2...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172622(((4R,5R)-3,3-Dibutyl-4-hydroxy-1,1-dioxo-5-phenyl-...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172628((4R,5R)-7-Amino-1,1-dioxo-5-phenyl-3,3-dipropyl-2,...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172639((3S,4R,5R)-3-Butyl-3-ethyl-7-hydroxyamino-1,1-diox...)
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172613((3S,4R,5R)-3-Butyl-3-ethyl-1,1-dioxo-5-phenyl-2,3,...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172642(Hexanoic acid ((3S,4R,5R)-3-butyl-3-ethyl-4-hydrox...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172616((4R,5R)-5-(4-Fluoro-phenyl)-7-methyl-1,1-dioxo-3,3...)
Affinity DataIC50: 318nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172643(((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1-dioxo-5-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172605((4R,5S)-7-Bromo-5-(2-bromo-phenyl)-3,3-dibutyl-1,1...)
Affinity DataIC50: 550nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172627(((4R,5R)-3,3-Dibutyl-4-hydroxy-1,1-dioxo-5-phenyl-...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172606(N-((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1-dioxo-...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172607(((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1-dioxo-5-...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172621((3S,4R,5R)-3-Butyl-3-ethyl-7-hexylamino-1,1-dioxo-...)
Affinity DataIC50: 1.67E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172620((4R,5R)-7-Benzylamino-3,3-dibutyl-1,1-dioxo-5-phen...)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172645((3S,4S,5S)-3-Butyl-3-ethyl-1,1-dioxo-5-phenyl-2,3,...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172638((3S,4R,5R)-3-Butyl-7-(N-hydroxy,N-ter-butoxycarbon...)
Affinity DataIC50: 2.67E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172630((4R,5R)-7-Amino-3,3-diethyl-1,1-dioxo-5-phenyl-2,3...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172626((3S,4S,5R)-3-Butyl-3-ethyl-1,1-dioxo-5-phenyl-2,3,...)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172614((3S,4R,5R)-3-Butyl-8-dec-9-enyloxy-3-ethyl-1,1-dio...)
Affinity DataIC50: 1.60E+4nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172602((2-{2-[2-((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172644([6-((3S,4R,5R)-3-Butyl-3-ethyl-4-hydroxy-1,1-dioxo...)
Affinity DataIC50: 2.10E+4nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172635((4R,5R)-7-Amino-3,3-dimethyl-1,1-dioxo-5-phenyl-2,...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in Baby hamster cells expressing human IBATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed