Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50037607
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 70nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50011181(CHEMBL666 | (PFA)dihydroxyphosphinecarboxylic acid...)
Affinity DataIC50: 280nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 300nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172526(1-Methyl-6-morpholin-4-ylmethyl-4-oxo-1,4-dihydro-...)
Affinity DataIC50: 370nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50090910(6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7...)
Affinity DataIC50: 400nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172518(2-(3-Hydroxy-propyl)-7-methyl-4-oxo-4,7-dihydro-th...)
Affinity DataIC50: 400nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 400nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172528(2-(4-Hydroxy-butyl)-7-methyl-4-oxo-4,7-dihydro-thi...)
Affinity DataIC50: 430nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172518(2-(3-Hydroxy-propyl)-7-methyl-4-oxo-4,7-dihydro-th...)
Affinity DataIC50: 460nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50090910(6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7...)
Affinity DataIC50: 500nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172518(2-(3-Hydroxy-propyl)-7-methyl-4-oxo-4,7-dihydro-th...)
Affinity DataIC50: 500nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50090910(6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7...)
Affinity DataIC50: 600nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172526(1-Methyl-6-morpholin-4-ylmethyl-4-oxo-1,4-dihydro-...)
Affinity DataIC50: 600nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50090910(6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7...)
Affinity DataIC50: 600nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172520(7-Ethyl-2-(3-hydroxy-propyl)-4-oxo-4,7-dihydro-thi...)
Affinity DataIC50: 670nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172526(1-Methyl-6-morpholin-4-ylmethyl-4-oxo-1,4-dihydro-...)
Affinity DataIC50: 700nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172534(7-(2-Hydroxy-ethyl)-2-(3-hydroxy-propyl)-4-oxo-4,7...)
Affinity DataIC50: 750nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 770nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172533(7-(2-Diethylamino-ethyl)-2-(3-hydroxy-propyl)-4-ox...)
Affinity DataIC50: 810nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172532(2-(3-Hydroxy-prop-1-ynyl)-7-methyl-4-oxo-4,7-dihyd...)
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172522(7-(2-Hydroxy-ethyl)-2-(3-hydroxy-prop-1-ynyl)-4-ox...)
Affinity DataIC50: 1.10E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 1.10E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 1.20E+3nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172516(7-(2-Diethylamino-ethyl)-2-(3-hydroxy-prop-1-ynyl)...)
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172535(7-Ethyl-2-(3-hydroxy-prop-1-ynyl)-4-oxo-4,7-dihydr...)
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172527(2-(3-Hydroxy-propyl)-4-oxo-4,7-dihydro-thieno[2,3-...)
Affinity DataIC50: 2.20E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 2.30E+3nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172519(2-(3-Hydroxy-propyl)-7-isopropyl-4-oxo-4,7-dihydro...)
Affinity DataIC50: 2.40E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50011181(CHEMBL666 | (PFA)dihydroxyphosphinecarboxylic acid...)
Affinity DataIC50: 2.50E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50090910(6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7...)
Affinity DataIC50: 2.60E+3nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172531(2-(3-Hydroxy-prop-1-ynyl)-4-oxo-4,7-dihydro-thieno...)
Affinity DataIC50: 2.70E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-1)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 3.30E+3nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172524(2-(2-Hydroxy-ethyl)-7-methyl-4-oxo-4,7-dihydro-thi...)
Affinity DataIC50: 4.00E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172515(2-(3-Hydroxy-prop-1-ynyl)-7-isopropyl-4-oxo-4,7-di...)
Affinity DataIC50: 4.20E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 5.80E+3nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 5.80E+3nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172529(2-(4-Hydroxy-but-1-ynyl)-7-methyl-4-oxo-4,7-dihydr...)
Affinity DataIC50: 9.50E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172523(2-(5-Hydroxy-pentyl)-7-methyl-4-oxo-4,7-dihydro-th...)
Affinity DataIC50: 9.70E+3nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 1.34E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172530(2-Hydroxymethyl-7-methyl-4-oxo-4,7-dihydro-thieno[...)
Affinity DataIC50: 1.85E+4nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50011181(CHEMBL666 | (PFA)dihydroxyphosphinecarboxylic acid...)
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50011181(CHEMBL666 | (PFA)dihydroxyphosphinecarboxylic acid...)
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172525(2-(5-Hydroxy-pent-1-ynyl)-7-methyl-4-oxo-4,7-dihyd...)
Affinity DataIC50: 2.20E+4nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-5)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 2.21E+4nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172518(2-(3-Hydroxy-propyl)-7-methyl-4-oxo-4,7-dihydro-th...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase catalytic subunit(HHV-3)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172517(PNU-181465 | N-(4-chlorobenzyl)-4-hydroxy-6-(3-hyd...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human delta DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50172514(7-Methyl-2-morpholin-4-ylmethyl-4-oxo-4,7-dihydro-...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 55 total ) | Next | Last >>
Jump to: