Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 1197
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9900(7-[(3-nitrophenyl)methoxy]-3-phenyl-2-[(pyridin-4-...)
Affinity DataIC50: 113nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9901(3-Phenyl-7-(4-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50: 132nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9899(3-Phenyl-7-(2-nitrophenylmethoxy)-2-[(4-pyridylmet...)
Affinity DataIC50: 138nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9906(3-Phenyl-7-(4-methoxyphenylmethoxy)-2-[(4-pyridylm...)
Affinity DataIC50: 161nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9909(7-[(4-bromophenyl)methoxy]-3-phenyl-2-[(pyridin-4-...)
Affinity DataIC50: 213nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9910(7-[(4-chlorophenyl)methoxy]-3-phenyl-2-[(pyridin-4...)
Affinity DataIC50: 233nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9905(3-Phenyl-7-(2-methoxyphenylmethoxy)-2-[(4-pyridylm...)
Affinity DataIC50: 243nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9908(7-[(4-fluorophenyl)methoxy]-3-phenyl-2-[(pyridin-4...)
Affinity DataIC50: 337nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9904(3-Phenyl-7-(phenylethoxy)-2-[(4-pyridylmethyl)thio...)
Affinity DataIC50: 359nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9912(3-phenyl-7-(pyridin-2-ylmethoxy)-2-[(pyridin-4-ylm...)
Affinity DataIC50: 378nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9907(7-(cyclohexylmethoxy)-3-phenyl-2-[(pyridin-4-ylmet...)
Affinity DataIC50: 553nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9911(3-phenyl-7-[(4-phenylphenyl)methoxy]-2-[(pyridin-4...)
Affinity DataKi:  39nM ΔG°:  -44.0kJ/mole IC50: 79nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9903(7-(naphthalen-2-ylmethoxy)-3-phenyl-2-[(pyridin-4-...)
Affinity DataKi:  74nM ΔG°:  -42.3kJ/mole IC50: 90nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9902(3-Phenyl-7-(alpha-naphthylmethoxy)-2-[(4-pyridylme...)
Affinity DataKi:  114nM ΔG°:  -41.2kJ/mole IC50: 112nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAromatase(Human)
Ohio State University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed