Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50016664
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 0.240nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 0.260nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171808(N-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171801(N-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171802(N-[3,5-Dichloro-4-(5-isopropyl-6-methoxy-naphthale...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171805([4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichlor...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171803(3-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171808(N-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171801(N-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171799([3,5-Dichloro-4-(6-hydroxy-5-methyl-naphthalen-1-y...)
Affinity DataIC50: 7.20nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171800([4-(3-Bromo-4-hydroxy-phenoxy)-3,5-dichloro-phenyl...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171797([4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichlor...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171803(3-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171802(N-[3,5-Dichloro-4-(5-isopropyl-6-methoxy-naphthale...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171805([4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichlor...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171798(N-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171806([3,5-Dichloro-4-(6-hydroxy-5-phenyl-naphthalen-1-y...)
Affinity DataIC50: 29nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171799([3,5-Dichloro-4-(6-hydroxy-5-methyl-naphthalen-1-y...)
Affinity DataIC50: 48nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171798(N-[4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichl...)
Affinity DataIC50: 62nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171797([4-(5-Bromo-6-hydroxy-naphthalen-1-yl)-3,5-dichlor...)
Affinity DataIC50: 101nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171800([4-(3-Bromo-4-hydroxy-phenoxy)-3,5-dichloro-phenyl...)
Affinity DataIC50: 109nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171806([3,5-Dichloro-4-(6-hydroxy-5-phenyl-naphthalen-1-y...)
Affinity DataIC50: 125nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171804([3,5-Dichloro-4-(6-hydroxy-naphthalen-1-yl)-phenyl...)
Affinity DataIC50: 545nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171804([3,5-Dichloro-4-(6-hydroxy-naphthalen-1-yl)-phenyl...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171807([3,5-Dichloro-4-(4-hydroxy-phenoxy)-phenyl]-acetic...)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50171807([3,5-Dichloro-4-(4-hydroxy-phenoxy)-phenyl]-acetic...)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed