Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with all data for entry = 50016633
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171421(3-(4-Chloro-phenyl)-5-furan-2-yl-[1,2,4]oxadiazole...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171420(5-(3-Chloro-4-methyl-thiophen-2-yl)-3-(4-chloro-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171435(3-(4-chloro-2-methylphenyl)-5-(3-chlorothiophen-2-...)
Affinity DataEC50:  380nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171413(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50:  1.61E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171409(5-(3-Chloro-thiophen-2-yl)-3-phenyl-[1,2,4]oxadiaz...)
Affinity DataEC50:  2.82E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171415(5-(3-Bromo-furan-2-yl)-3-(4-trifluoromethyl-phenyl...)
Affinity DataEC50:  2.01E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171429(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171436(5-Chloro-2-[5-(3-chloro-furan-2-yl)-[1,2,4]oxadiaz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase activation activity of compound in cell line H-1299 nonsmall-cell lung cancer cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171428(cid_784811 | CHEMBL191015 | 5-Thiophen-2-yl-3-p-to...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171422(5-(3-chlorothiophen-2-yl)-3-(3,4-dichlorophenyl)-1...)
Affinity DataEC50:  1.41E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171433(2-[5-(3-Chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-y...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171436(5-Chloro-2-[5-(3-chloro-furan-2-yl)-[1,2,4]oxadiaz...)
Affinity DataEC50:  580nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171418(3-(4-Chloro-phenyl)-5-thiophen-2-yl-[1,2,4]oxadiaz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171413(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in P338 cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  760nMAssay Description:Caspase-3 activation activity tested in HT-29 cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171427(5-[5-(3-Chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-y...)
Affinity DataEC50:  920nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171437(5-(3-Chloro-thiophen-2-yl)-3-(4-chloro-3-trifluoro...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171427(5-[5-(3-Chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-y...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171435(3-(4-chloro-2-methylphenyl)-5-(3-chlorothiophen-2-...)
Affinity DataEC50:  910nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171434(5-(2-Chloro-phenyl)-3-(4-trifluoromethyl-phenyl)-[...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171430(3-(4-Chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-[1,...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171429(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50:  610nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171424(5-(3-Bromo-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]...)
Affinity DataEC50:  830nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171415(5-(3-Bromo-furan-2-yl)-3-(4-trifluoromethyl-phenyl...)
Affinity DataEC50:  1.07E+3nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171431(3-(4-Chloro-phenyl)-5-(3-ethoxy-thiophen-2-yl)-[1,...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171426(5-(2-Chloro-phenyl)-3-(4-chloro-phenyl)-[1,2,4]oxa...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171436(5-Chloro-2-[5-(3-chloro-furan-2-yl)-[1,2,4]oxadiaz...)
Affinity DataEC50:  1.11E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171433(2-[5-(3-Chloro-thiophen-2-yl)-[1,2,4]oxadiazol-3-y...)
Affinity DataEC50:  410nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171421(3-(4-Chloro-phenyl)-5-furan-2-yl-[1,2,4]oxadiazole...)
Affinity DataEC50:  1.74E+4nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171428(cid_784811 | CHEMBL191015 | 5-Thiophen-2-yl-3-p-to...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171420(5-(3-Chloro-4-methyl-thiophen-2-yl)-3-(4-chloro-ph...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171422(5-(3-chlorothiophen-2-yl)-3-(3,4-dichlorophenyl)-1...)
Affinity DataEC50:  370nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171431(3-(4-Chloro-phenyl)-5-(3-ethoxy-thiophen-2-yl)-[1,...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171435(3-(4-chloro-2-methylphenyl)-5-(3-chlorothiophen-2-...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171414(5-Chloro-2-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxad...)
Affinity DataEC50:  1.59E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171431(3-(4-Chloro-phenyl)-5-(3-ethoxy-thiophen-2-yl)-[1,...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171432(2-Chloro-5-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxad...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171425(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethoxy-p...)
Affinity DataEC50:  890nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171423(5-(3-Bromo-thiophen-2-yl)-3-(4-chloro-phenyl)-[1,2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171437(5-(3-Chloro-thiophen-2-yl)-3-(4-chloro-3-trifluoro...)
Affinity DataEC50:  930nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171432(2-Chloro-5-[5-(3-chloro-thiophen-2-yl)-[1,2,4]oxad...)
Affinity DataEC50:  290nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171430(3-(4-Chloro-phenyl)-5-(3-chloro-thiophen-2-yl)-[1,...)
Affinity DataEC50:  1.77E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171410(5-(3-Chloro-thiophen-2-yl)-3-p-tolyl-[1,2,4]oxadia...)
Affinity DataEC50:  3.66E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171437(5-(3-Chloro-thiophen-2-yl)-3-(4-chloro-3-trifluoro...)
Affinity DataEC50:  560nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171418(3-(4-Chloro-phenyl)-5-thiophen-2-yl-[1,2,4]oxadiaz...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171424(5-(3-Bromo-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]...)
Affinity DataEC50:  1.08E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171415(5-(3-Bromo-furan-2-yl)-3-(4-trifluoromethyl-phenyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171417(5-(3-Chloro-thiophen-2-yl)-3-(3-trifluoromethyl-ph...)
Affinity DataEC50:  280nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171421(3-(4-Chloro-phenyl)-5-furan-2-yl-[1,2,4]oxadiazole...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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