Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50016525
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170047((4-Hydroxy-3-iodo-5-methoxy-phenyl)-acetic acid (2...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170053(N-(4-hydroxy-2-iodo-5-methoxybenzyl)nonanamide | N...)
Affinity DataIC50: 10nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170062(Nonanoic acid 2-bromo-4-hydroxy-5-methoxy-benzylam...)
Affinity DataIC50: 16nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170061((E)-Octadec-9-enal | CHEMBL190707)
Affinity DataIC50: 35nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170054(Nonanoic acid 2-chloro-4-hydroxy-5-methoxy-benzyla...)
Affinity DataIC50: 50nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170065((5E,8E,11E,14E)-Icosa-5,8,11,14-tetraenal | CHEMBL...)
Affinity DataIC50: 51nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM20284(N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170066(Nonanoic acid 4-hydroxy-3-iodo-5-methoxy-benzylami...)
Affinity DataIC50: 126nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170063(Nonanoic acid 3-bromo-4-hydroxy-5-methoxy-benzylam...)
Affinity DataIC50: 252nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170049(Nonanoic acid 3-ethyl-4-hydroxy-5-methoxy-benzylam...)
Affinity DataIC50: 355nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170059(Nonanoic acid 4-hydroxy-3-methoxy-5-vinyl-benzylam...)
Affinity DataIC50: 390nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170050(Nonanoic acid 3-chloro-4-hydroxy-5-methoxy-benzyla...)
Affinity DataIC50: 631nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170048(Nonanoic acid 3-ethynyl-4-hydroxy-5-methoxy-benzyl...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170056(Nonanoic acid 4-hydroxy-2-iodo-3-methoxy-benzylami...)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170058(7-Hydroxy-8-methoxy-3-nonanoyl-3,4-dihydro-1H-quin...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170055(3-[5-Hydroxy-4-methoxy-2-(nonanoylamino-methyl)-ph...)
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170052(Nonanoic acid 2-acetylamino-4-hydroxy-3-methoxy-be...)
Affinity DataIC50: 9.54E+3nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170060(Nonanoic acid 3-acetyl-4-hydroxy-5-methoxy-benzyla...)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170057(Nonanoic acid 4-hydroxy-3-methoxy-2-nitro-benzylam...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170067((2E,4E,6E,8E)-9-(6,6-Dimethyl-cyclohex-1-enyl)-3,7...)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170064(Nonanoic acid [6,2'-dihydroxy-5,3'-dimethoxy-5'-(n...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1; (weak agonist activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
University of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50170051(Nonanoic acid (6-hydroxy-5-methoxy-biphenyl-3-ylme...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in HEK293 cells expressing human TRPV1; (weak agonist activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed