Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50016335
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167861(N-(4-Iodo-benzo[b]thiophene-2-carbonyl)-guanidine;...)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167865(N-(4-Chloro-benzo[b]thiophene-2-carbonyl)-guanidin...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167856(N-(4-Bromo-benzo[b]thiophene-2-carbonyl)-guanidine...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167841(N-(4-Ethyl-benzo[b]thiophene-2-carbonyl)-guanidine...)
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167846(N-(4-Vinyl-benzo[b]thiophene-2-carbonyl)-guanidine...)
Affinity DataIC50: 310nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167845(N-(4-Trifluoromethyl-benzo[b]thiophene-2-carbonyl)...)
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167863(N-(4-Methyl-benzo[b]thiophene-2-carbonyl)-guanidin...)
Affinity DataIC50: 480nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167867(N-[4-(3,5-Dichloro-phenyl)-benzo[b]thiophene-2-car...)
Affinity DataIC50: 680nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 680nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167839(N-(4-Isopropyl-benzo[b]thiophene-2-carbonyl)-guani...)
Affinity DataIC50: 850nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167852(N-(4-Fluoro-benzo[b]thiophene-2-carbonyl)-guanidin...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167868(N-(4-Cyano-benzo[b]thiophene-2-carbonyl)-guanidine...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167847(N-(4-Nitro-benzo[b]thiophene-2-carbonyl)-guanidine...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167850(N-[4-(3-Chloro-phenyl)-benzo[b]thiophene-2-carbony...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167866(N-[4-(3-Chloro-4-fluoro-phenyl)-benzo[b]thiophene-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167848(N-(4-m-Tolyl-benzo[b]thiophene-2-carbonyl)-guanidi...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167843(N-(4-Methoxy-benzo[b]thiophene-2-carbonyl)-guanidi...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167840(N-[4-(4-Fluoro-phenyl)-benzo[b]thiophene-2-carbony...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167851(N-[4-(2-Chloro-phenyl)-benzo[b]thiophene-2-carbony...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167857(N-[4-(3-Trifluoromethyl-phenyl)-benzo[b]thiophene-...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167844(N-[4-(3,5-Difluoro-phenyl)-benzo[b]thiophene-2-car...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167842(N-[4-(3-Fluoro-phenyl)-benzo[b]thiophene-2-carbony...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167862(N-(4-o-Tolyl-benzo[b]thiophene-2-carbonyl)-guanidi...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167864(N-(4-Phenyl-benzo[b]thiophene-2-carbonyl)-guanidin...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167849(N-[4-(2,5-Difluoro-phenyl)-benzo[b]thiophene-2-car...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167858(N-[4-(2,3-Difluoro-phenyl)-benzo[b]thiophene-2-car...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167860(N-[4-(2-Fluoro-phenyl)-benzo[b]thiophene-2-carbony...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167855(N-[4-(3-Methoxy-phenyl)-benzo[b]thiophene-2-carbon...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167838(N-(Benzo[b]thiophene-2-carbonyl)-guanidine; compou...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167859(N-(4-Amino-benzo[b]thiophene-2-carbonyl)-guanidine...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167854(N-(4-p-Tolyl-benzo[b]thiophene-2-carbonyl)-guanidi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167853(N-[4-(4-Chloro-phenyl)-benzo[b]thiophene-2-carbony...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed