Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 2921
LigandPNGBDBM26078(2-(carbamoylamino)-5-{2-[5-(hydroxymethyl)thiophen...)
Affinity DataIC50: 195nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26087(2-(carbamoylamino)-5-(2-cyclopropylethynyl)thiophe...)
Affinity DataIC50: 273nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26086(2-(carbamoylamino)-5-[2-(3-hydroxyphenyl)ethynyl]t...)
Affinity DataIC50: 303nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26082(2-(carbamoylamino)-5-[2-(3-fluorophenyl)ethynyl]th...)
Affinity DataIC50: 331nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26081(2-(carbamoylamino)-5-[2-(5-cyanothiophen-3-yl)ethy...)
Affinity DataIC50: 333nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26077(2-(carbamoylamino)-5-[2-(thiophen-3-yl)ethynyl]thi...)
Affinity DataIC50: 420nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26097(2-(carbamoylamino)-5-[2-(3-methanesulfonamidopheny...)
Affinity DataIC50: 454nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26079(2-(carbamoylamino)-5-{2-[5-(1-hydroxypropyl)thioph...)
Affinity DataIC50: 465nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26090(N-(3-{2-[4-carbamoyl-5-(carbamoylamino)thiophen-2-...)
Affinity DataIC50: 557nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26080(2-(carbamoylamino)-5-{2-[5-(1-hydroxy-2-methylprop...)
Affinity DataIC50: 563nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26083(2-(carbamoylamino)-5-[2-(2-fluorophenyl)ethynyl]th...)
Affinity DataIC50: 620nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26092(5-[2-(3-benzamidophenyl)ethynyl]-2-(carbamoylamino...)
Affinity DataIC50: 704nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26088(5-[2-(3-aminophenyl)ethynyl]-2-(carbamoylamino)thi...)
Affinity DataIC50: 709nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26085(2-(carbamoylamino)-5-[2-(2-methylphenyl)ethynyl]th...)
Affinity DataIC50: 716nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26093(2-(carbamoylamino)-5-[2-(3-acetamidophenyl)ethynyl...)
Affinity DataIC50: 964nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26094(2-(carbamoylamino)-5-{2-[3-(2,2,2-trifluoroacetami...)
Affinity DataIC50: 980nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26084(2-(carbamoylamino)-5-[2-(2-chlorophenyl)ethynyl]th...)
Affinity DataIC50: 1.01E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26091(N-(3-{2-[4-carbamoyl-5-(carbamoylamino)thiophen-2-...)
Affinity DataIC50: 1.85E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26095(2-(carbamoylamino)-5-(2-{3-[2-(dimethylamino)aceta...)
Affinity DataIC50: 1.88E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26096(methyl N-{2-[(3-{2-[4-carbamoyl-5-(carbamoylamino)...)
Affinity DataIC50: 4.40E+3nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26098(3-amino-5-(thiophen-3-yl)thiophene-2-carboxamide |...)
Affinity DataIC50: 1.12E+4nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
LigandPNGBDBM26089(N-(3-{2-[4-carbamoyl-5-(carbamoylamino)thiophen-2-...)
Affinity DataIC50: 2.00E+4nMpH: 7.6 T: 2°CAssay Description:The inhibitory effect of test compounds on kinase activity was measured using a biotinylated I-Kappa-B-alpha peptide and increasing doses of inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed