Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50016220
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152799((R)-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(2-(1-(pi...)
Affinity DataEC50:  4.70nMAssay Description:Agonistic effective concentration to stimulate cAMP in CHO cells stably expressing the human melanocortin-4 receptor More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166520(1-Cyclopentyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166533(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166523(Pyrrolidine-1-carboxylic acid [(R)-1-(2,4-dichloro...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166544(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166525(3-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  2nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166534(4-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  2nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166540(1-Cyclopropyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166519((R)-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(t...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166539(1-tert-Butyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166535(N-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166532(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166537(N-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166521([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166524([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  4.5nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166538([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166530(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  5nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166543([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  5nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166529((+/-)-1-[2-(4-fluorophenyl)-2-(4-isopropylpiperazi...)
Affinity DataKi:  7.90nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166545(N-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  14nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155370(Piperidine-3-carboxylic acid [(R)-1-(4-chloro-benz...)
Affinity DataKi:  15nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166542((R)-3-(2,4-Dichloro-phenyl)-2-[(thiazol-2-ylmethyl...)
Affinity DataKi:  16nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166528((R)-2-(Cyclopropylmethyl-amino)-3-(2,4-dichloro-ph...)
Affinity DataKi:  18nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166518((R)-2-(2-Amino-ethylamino)-3-(2,4-dichloro-phenyl)...)
Affinity DataKi:  18nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155390(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  21nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166541([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  23nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166548((R)-3-(2,4-Dichloro-phenyl)-2-isobutylamino-1-(4-{...)
Affinity DataKi:  23nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166546((R)-2-Benzylamino-3-(2,4-dichloro-phenyl)-1-(4-{2-...)
Affinity DataKi:  31nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166536((R)-2-Amino-3-(2,4-dichloro-phenyl)-1-(4-{2-[(2-th...)
Affinity DataKi:  94nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166523(Pyrrolidine-1-carboxylic acid [(R)-1-(2,4-dichloro...)
Affinity DataKi:  160nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50142895(2-phenylimidazoline | ML-253764 | 2-{2-[2-(5-Bromo...)
Affinity DataKi:  160nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166544(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  300nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166525(3-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  350nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166532(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  350nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166532(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  390nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166547([(R)-1-Naphthalen-1-ylmethyl-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  420nMAssay Description:Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166533(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  450nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166525(3-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  560nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166521([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  560nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166519((R)-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(t...)
Affinity DataKi:  570nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166520(1-Cyclopentyl-3-[(R)-1-(2,4-dichloro-benzyl)-2-oxo...)
Affinity DataKi:  580nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50158484(3-Amino-N-[(R)-1-(2,4-dichloro-benzyl)-2-oxo-2-(4-...)
Affinity DataKi:  640nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166523(Pyrrolidine-1-carboxylic acid [(R)-1-(2,4-dichloro...)
Affinity DataKi:  670nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166524([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  680nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166519((R)-N-(3-(2,4-dichlorophenyl)-1-oxo-1-(4-(2-((2-(t...)
Affinity DataKi:  730nMAssay Description:Binding affinity at melanocortin-5 receptor stably transfected in HEK 293 cells using [125I]NDP-MSH as radiolabeledMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166544(1-[(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-t...)
Affinity DataKi:  790nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166521([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  790nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166538([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  800nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50166543([(R)-1-(2,4-Dichloro-benzyl)-2-oxo-2-(4-{2-[(2-thi...)
Affinity DataKi:  810nMAssay Description:Binding affinity for melanocortin-3 receptor transfected in HEK 293 cells using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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