Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50016163
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165781((R)-7-Benzyl-2-chloro-5-ethyl-3-(4-hydroxy-benzyl)...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165771((R)-7-Benzyl-2-bromo-5-ethyl-3-(4-hydroxy-benzyl)-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165773((R)-7-Benzyl-5-ethyl-3-(4-hydroxy-benzyl)-2-iodo-7...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50140595((R)-2,7-Dibenzyl-5-ethyl-7,8-dihydro-1H,5H-imidazo...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165787((R)-7-Benzyl-5-ethyl-3-(4-hydroxy-benzyl)-2-phenyl...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165782(5-Ethyl-1-(4-hydroxy-benzyl)-2-phenylethynyl-7-((R...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165795(2-Bromo-5-ethyl-1-(4-hydroxy-benzyl)-7-((R)-phenyl...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165778((R)-7-Benzyl-5-ethyl-3-(4-methoxy-benzyl)-2-phenyl...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165784((R)-7-Benzyl-5-ethyl-3-(4-hydroxy-benzyl)-2-methyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059029((6aR,9aS)-5-ethyl-5,6a,7,8,9,9a-hexahydro-2-(pheny...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165792((R)-7-Benzyl-5-ethyl-1-(4-methoxy-benzyl)-2-phenyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165772((R)-2,7-Dibenzyl-5-isopropyl-7,8-dihydro-1H,5H-imi...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165776((R)-7-Benzyl-2-bromo-5-ethyl-3-(4-methoxy-benzyl)-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165793(2-Benzyl-5-ethyl-1-(4-hydroxy-benzyl)-7-((R)-pheny...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165791((R)-2-Benzyl-5-ethyl-7-isopropyl-7,8-dihydro-1H,5H...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165786((R)-2,7-Dibenzyl-5-ethyl-3-(4-hydroxy-benzyl)-7,8-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165783((R)-1,2,7-Tribenzyl-5-ethyl-7,8-dihydro-1H,5H-imid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165768((R)-2-Benzyl-5,7-diethyl-7,8-dihydro-1H,5H-imidazo...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165767((R)-1,7-Dibenzyl-5-ethyl-2-phenylethynyl-7,8-dihyd...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human phosphodiesterase 11More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165780((R)-1,2-Dibenzyl-5-ethyl-7-propyl-7,8-dihydro-1H,5...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165789((R)-2,7-Dibenzyl-5-ethyl-1-(4-methoxy-benzyl)-7,8-...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165790((R)-1,2-Dibenzyl-5-ethyl-7-phenyl-7,8-dihydro-1H,5...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165779((R)-3,7-Dibenzyl-5-ethyl-2-phenylethynyl-7,8-dihyd...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165774((R)-7-Benzyl-2-bromo-5-ethyl-1-(4-methoxy-benzyl)-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165775((R)-2-Benzyl-5-ethyl-7-propyl-7,8-dihydro-1H,5H-im...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165770((R)-1,7-Dibenzyl-2-chloro-5-ethyl-7,8-dihydro-1H,5...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165794((R)-1,7-Dibenzyl-5-ethyl-2-phenethyl-7,8-dihydro-1...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059037(2-benzyl-5-methyl-(6aR,9aS)-1,4,5,8-tetrahydrocycl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165788((R)-2,7-Dibenzyl-5-methyl-7,8-dihydro-1H,5H-imidaz...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human phosphodiesterase 11More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165769((R)-2,7-Dibenzyl-5-ethyl-3-(4-methoxy-benzyl)-7,8-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165777((R)-1,7-Dibenzyl-2-bromo-5-ethyl-7,8-dihydro-1H,5H...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165785((R)-1,7-Dibenzyl-5-ethyl-7,8-dihydro-1H,5H-imidazo...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Phosphodiesterase 9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165771((R)-7-Benzyl-2-bromo-5-ethyl-3-(4-hydroxy-benzyl)-...)
Affinity DataIC50: 540nMAssay Description:Inhibition of human phosphodiesterase 11More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 790nMAssay Description:Inhibitory concentration against human phosphodiesterase 10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165771((R)-7-Benzyl-2-bromo-5-ethyl-3-(4-hydroxy-benzyl)-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration against human phosphodiesterase 10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human phosphodiesterase 11More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against human phosphodiesterase 10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Phosphodiesterase 9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Phosphodiesterase 9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165771((R)-7-Benzyl-2-bromo-5-ethyl-3-(4-hydroxy-benzyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Phosphodiesterase 9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human phosphodiesterase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human phosphodiesterase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against human phosphodiesterase 10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50165771((R)-7-Benzyl-2-bromo-5-ethyl-3-(4-hydroxy-benzyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human phosphodiesterase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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