Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50037577
TargetSodium-dependent dopamine transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098(CHEMBL542556 | METHYLPHENIDATE | (S)-Phenyl-(S)-pi...)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098(CHEMBL542556 | METHYLPHENIDATE | (S)-Phenyl-(S)-pi...)
Affinity DataIC50: 51nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211(Phenyl-piperidin-2-yl-acetic acid ethyl ester; hyd...)
Affinity DataIC50: 95nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098(CHEMBL542556 | METHYLPHENIDATE | (S)-Phenyl-(S)-pi...)
Affinity DataIC50: 122nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 289nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 289nMAssay Description:Inhibition of [3H]5-HT uptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211(Phenyl-piperidin-2-yl-acetic acid ethyl ester; hyd...)
Affinity DataIC50: 319nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 367nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 433nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 462nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211(Phenyl-piperidin-2-yl-acetic acid ethyl ester; hyd...)
Affinity DataIC50: 480nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098(CHEMBL542556 | METHYLPHENIDATE | (S)-Phenyl-(S)-pi...)
Affinity DataIC50: 788nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 2.99E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211(Phenyl-piperidin-2-yl-acetic acid ethyl ester; hyd...)
Affinity DataIC50: 7.20E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211(Phenyl-piperidin-2-yl-acetic acid ethyl ester; hyd...)
Affinity DataIC50: 7.54E+3nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211(Phenyl-piperidin-2-yl-acetic acid ethyl ester; hyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5-HT uptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098(CHEMBL542556 | METHYLPHENIDATE | (S)-Phenyl-(S)-pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed