Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50016078
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164750([2-(3-Benzyl-3H-inden-1-yl)-ethyl]-methyl-amine | ...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164758([2-(1-Benzyl-1H-indol-3-yl)-ethyl]-dimethyl-amine ...)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164756(Dimethyl-[2-(1-phenethyl-1H-indol-3-yl)-ethyl]-ami...)
Affinity DataKi:  12nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164759([2-(3-Benzyl-indol-1-yl)-ethyl]-dimethyl-amine | C...)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164752(4-[1-(2-Dimethylamino-ethyl)-1H-indol-3-ylmethyl]-...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164746(Dimethyl-(2-{3-[1-phenyl-meth-(E)-ylidene]-3H-inde...)
Affinity DataKi:  57nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164754(Methyl-[2-(3-phenethyl-3H-inden-1-yl)-ethyl]-amine...)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164749(CHEMBL193376 | cid_98148 | 4-Inden-(1E)-ylidenemet...)
Affinity DataKi:  640nM ΔG°:  -35.4kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164755(4-(Indane-1-sulfonyl)-phenylamine | CHEMBL191972)
Affinity DataKi:  740nM ΔG°:  -35.0kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164747(4-(1H-Indol-3-ylmethyl)-phenylamine | CHEMBL364248)
Affinity DataKi:  2.53E+3nM ΔG°:  -31.9kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164748(4-(Indan-1-ylsulfanyl)-phenylamine | CHEMBL191844)
Affinity DataKi:  4.20E+3nM ΔG°:  -30.7kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164753(4-(1H-Inden-1-ylmethyl)-phenylamine | CHEMBL193637)
Affinity DataKi:  4.47E+3nM ΔG°:  -30.5kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164751(4-Indan-1-ylmethyl-phenylamine | CHEMBL364089)
Affinity DataKi:  6.10E+3nM ΔG°:  -29.8kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50164757(4-(3H-Inden-1-ylmethyl)-phenylamine | CHEMBL371048)
Affinity DataKi:  1.18E+4nM ΔG°:  -28.1kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity against human 5-Hydroxytryptamine 6 receptor expressed in HEK293 cells using [3H]LSD done for 90 minutes at pH 7.4 at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed