Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 1221
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10216(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thi...)
Affinity DataIC50: 4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10218(phenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-th...)
Affinity DataIC50: 4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10216(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thi...)
Affinity DataIC50: 4.60E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10219(BI-9B11 | [2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,...)
Affinity DataIC50: 5.50E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10218(phenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-th...)
Affinity DataIC50: 6.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50: 6.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10219(BI-9B11 | [2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,...)
Affinity DataIC50: 6.20E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50: 7.40E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50: 7.50E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10223(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methy...)
Affinity DataIC50: 8.20E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50: 1.28E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50: 1.29E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50: 1.33E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50: 1.50E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50: 1.70E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10218(phenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-th...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10223(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10220(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10217(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N-(furan-2-yl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10219(BI-9B11 | [2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10225(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methyl-1,3-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10224(4-{[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiaz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10223(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-methy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10222(4-chlorophenyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10221(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-N,N-dimethyl-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  2.70E+3nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-3(Human)
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  4.30E+3nM ΔG°:  -30.3kJ/molepH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-7(Human)
Burnham Institute

LigandPNGBDBM10215(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4-[3-(trifluo...)
Affinity DataKi:  6.20E+3nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCaspase-8(Human)
Burnham Institute

LigandPNGBDBM10216(ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thi...)
Affinity DataKi:  3.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed