Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 1339
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10947(bis(18)-HupB | (1R,10R)-16-methyl-14-{3-[methyl({1...)
Affinity DataIC50: 4.93nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10946((1R,10R)-16-methyl-14-{3-[methyl({8-[methyl({3-[(1...)
Affinity DataIC50: 18.5nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10948(bis(20)-HupB | (1R,10R)-16-methyl-14-{3-[methyl({1...)
Affinity DataIC50: 25.2nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10945(bis(14)-HupB | (1R,10R)-16-methyl-14-{3-[methyl({6...)
Affinity DataIC50: 35.9nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10944((1R,10R)-16-methyl-14-{2-[methyl({8-[methyl({2-[(1...)
Affinity DataIC50: 50.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10441((+)-Huperzine A | (13E)-1-amino-13-ethylidene-11-m...)
Affinity DataIC50: 72.4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10943(bis(12)-HupB | (1R,10R)-16-methyl-14-{2-[methyl({6...)
Affinity DataIC50: 76.2nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10942(bis(9)-Hup B | (1R,10R)-16-methyl-14-{2-[methyl({3...)
Affinity DataIC50: 471nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10941((1R,10R)-16-methyl-14-{2-[methyl({2-[methyl({2-[(1...)
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10632((1R,10R)-16-methyl-6,14-diazatetracyclo[7.5.3.0^{1...)
Affinity DataIC50: 1.93E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10947(bis(18)-HupB | (1R,10R)-16-methyl-14-{3-[methyl({1...)
Affinity DataIC50: 5.43E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10942(bis(9)-Hup B | (1R,10R)-16-methyl-14-{2-[methyl({3...)
Affinity DataIC50: 6.00E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10946((1R,10R)-16-methyl-14-{3-[methyl({8-[methyl({3-[(1...)
Affinity DataIC50: 6.30E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10943(bis(12)-HupB | (1R,10R)-16-methyl-14-{2-[methyl({6...)
Affinity DataIC50: 6.45E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10944((1R,10R)-16-methyl-14-{2-[methyl({8-[methyl({2-[(1...)
Affinity DataIC50: 6.54E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10945(bis(14)-HupB | (1R,10R)-16-methyl-14-{3-[methyl({6...)
Affinity DataIC50: 6.79E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10441((+)-Huperzine A | (13E)-1-amino-13-ethylidene-11-m...)
Affinity DataIC50: 7.02E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10948(bis(20)-HupB | (1R,10R)-16-methyl-14-{3-[methyl({1...)
Affinity DataIC50: 8.84E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Shanghai Institute of Materia Medica

LigandPNGBDBM10632((1R,10R)-16-methyl-6,14-diazatetracyclo[7.5.3.0^{1...)
Affinity DataIC50: 2.27E+5nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed