Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 1887
LigandPNGBDBM14797(ethyl 1-(2-chlorophenyl)-3,5-dimethyl-1H-pyrazole-...)
Affinity DataIC50: 19nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14798(ethyl 3,5-dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4...)
Affinity DataIC50: 21nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14798(ethyl 3,5-dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4...)
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14797(ethyl 1-(2-chlorophenyl)-3,5-dimethyl-1H-pyrazole-...)
Affinity DataIC50: 56nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14796(ethyl 1-(4-aminophenyl)-3,5-dimethyl-1H-pyrazole-4...)
Affinity DataIC50: 160nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14785(ethyl 3,5-dimethyl-1-phenyl-1H-pyrazole-4-carboxyl...)
Affinity DataIC50: 270nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14785(ethyl 3,5-dimethyl-1-phenyl-1H-pyrazole-4-carboxyl...)
Affinity DataIC50: 310nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14796(ethyl 1-(4-aminophenyl)-3,5-dimethyl-1H-pyrazole-4...)
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14795(ethyl 3,5-dimethyl-1-(4-nitrophenyl)-1H-pyrazole-4...)
Affinity DataIC50: 840nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14786(ethyl 3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-ca...)
Affinity DataIC50: 880nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14795(ethyl 3,5-dimethyl-1-(4-nitrophenyl)-1H-pyrazole-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14786(ethyl 3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-ca...)
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14794(ethyl 1-(4-methoxyphenyl)-3,5-dimethyl-1H-pyrazole...)
Affinity DataIC50: 2.00E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14790(ethyl 1-(2,4-dinitrophenyl)-3,5-dimethyl-1H-pyrazo...)
Affinity DataIC50: 4.60E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14794(ethyl 1-(4-methoxyphenyl)-3,5-dimethyl-1H-pyrazole...)
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14793(ethyl 3,5-dimethyl-1-(4-sulfamoylphenyl)-1H-pyrazo...)
Affinity DataIC50: 9.10E+3nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14793(ethyl 3,5-dimethyl-1-(4-sulfamoylphenyl)-1H-pyrazo...)
Affinity DataIC50: 1.30E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14792(ethyl 1-(4-tert-butylphenyl)-3,5-dimethyl-1H-pyraz...)
Affinity DataIC50: 1.40E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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LigandPNGBDBM14784(ethyl 3-amino-5-(4-methoxyphenyl)-1H-pyrazole-4-ca...)
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14787(ethyl 3,5-dimethyl-1-(quinolin-8-yl)-1H-pyrazole-4...)
Affinity DataIC50: 1.70E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14790(ethyl 1-(2,4-dinitrophenyl)-3,5-dimethyl-1H-pyrazo...)
Affinity DataIC50: 1.70E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14792(ethyl 1-(4-tert-butylphenyl)-3,5-dimethyl-1H-pyraz...)
Affinity DataIC50: 1.90E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14784(ethyl 3-amino-5-(4-methoxyphenyl)-1H-pyrazole-4-ca...)
Affinity DataIC50: 1.90E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14787(ethyl 3,5-dimethyl-1-(quinolin-8-yl)-1H-pyrazole-4...)
Affinity DataIC50: 1.90E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14791(ethyl 3,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]-...)
Affinity DataIC50: 2.10E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14788(ethyl 5-amino-1-{8-thia-4,6-diazatricyclo[7.4.0.0^...)
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14791(ethyl 3,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]-...)
Affinity DataIC50: 3.20E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14788(ethyl 5-amino-1-{8-thia-4,6-diazatricyclo[7.4.0.0^...)
Affinity DataIC50: 5.00E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14779(ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate | Pyr...)
Affinity DataIC50: 6.00E+4nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14779(ethyl 3,5-dimethyl-1H-pyrazole-4-carboxylate | Pyr...)
Affinity DataIC50: 8.20E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14789(ethyl 1-[3,5-bis(trifluoromethyl)phenyl]-3,5-dimet...)
Affinity DataIC50: 9.70E+4nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14789(ethyl 1-[3,5-bis(trifluoromethyl)phenyl]-3,5-dimet...)
Affinity DataIC50: 1.60E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14783(methyl 3-methyl-5-(5-methyl-1,2-oxazol-3-yl)-1H-py...)
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14781(ethyl 3-amino-1H-pyrazole-4-carboxylate | Pyrazole...)
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14780(ethyl 3-methyl-1H-pyrazole-4-carboxylate | Pyrazol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14778(3,5-dimethyl-1H-pyrazole-4-carboxylic acid | Pyraz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14783(methyl 3-methyl-5-(5-methyl-1,2-oxazol-3-yl)-1H-py...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14782(5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14781(ethyl 3-amino-1H-pyrazole-4-carboxylate | Pyrazole...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14780(ethyl 3-methyl-1H-pyrazole-4-carboxylate | Pyrazol...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14778(3,5-dimethyl-1H-pyrazole-4-carboxylic acid | Pyraz...)
Affinity DataIC50: 2.00E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed