Compile Data Set for Download or QSAR
Report error Found 123 Enz. Inhib. hit(s) with all data for entry = 50015535
LigandPNGBDBM50157236(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157235(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  285nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157240(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  90nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157239(2''-Cyano-5''-[(4-cyano-benzyloxy)-(3-methyl-3H-im...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157242(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157247(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  120nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157237(2'',3''-Dichloro-5-[(4-cyano-benzyloxy)-(3-methyl-...)
Affinity DataEC50:  240nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  420nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157252(5-[(3-Fluoro-4-trifluoromethyl-benzyloxy)-(3-methy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157255(2'',4''-Dichloro-5-[(4-cyano-benzyloxy)-(3-methyl-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157254(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  85nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157256(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  89nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17325(CHEMBL29982 | (2S)-2-[(4-{[butyl(2-cyclohexylethyl...)
Affinity DataEC50:  16nMAssay Description:Effective concentration against H-ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157260(2-(4-Acetyl-piperazin-1-yl)-6-[(6-cyano-2''-triflu...)
Affinity DataEC50:  130nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157259(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  110nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157238(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  53nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13389(CHEMBL41748 | 4-{[(4-cyanophenyl)methoxy](1-methyl...)
Affinity DataEC50:  110nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157258(N-(1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biph...)
Affinity DataEC50:  330nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157273((R)-1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-bip...)
Affinity DataEC50:  210nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157253(5-[(4-Fluoro-3-trifluoromethyl-benzyloxy)-(3-methy...)
Affinity DataEC50:  100nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157249(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157250(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  170nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157270(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataEC50:  13nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157277(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  30nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126343(5-[Benzyloxy-(3-methyl-3H-imidazol-4-yl)-methyl]-2...)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against H-ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157267(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  201nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM13389(CHEMBL41748 | 4-{[(4-cyanophenyl)methoxy](1-methyl...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157254(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157235(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Farnesyl transferase inhibitor (ABT-839)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17325(CHEMBL29982 | (2S)-2-[(4-{[butyl(2-cyclohexylethyl...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157238(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157256(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157277(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157270(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157237(2'',3''-Dichloro-5-[(4-cyano-benzyloxy)-(3-methyl-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157258(N-(1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biph...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157285(5-[(3,4-Dichloro-benzyloxy)-(3-methyl-3H-imidazol-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157259(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157250(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157249(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157260(2-(4-Acetyl-piperazin-1-yl)-6-[(6-cyano-2''-triflu...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157240(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157247(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157273((R)-1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-bip...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157253(5-[(4-Fluoro-3-trifluoromethyl-benzyloxy)-(3-methy...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157257(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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